ANTIDIABETIC ACTIVITY OF TERMINALIA BELLIRICA ON ALLOXAN INDUCED DIABETIC RATS

Diabetes mellitus is one of the common metabolic disorders and 10% of the population. Suffer from this disease throughout the world. Insulin and oral hypoglycemic agents are still the major players in the management of the disease but many adverse effects were, observed and they did not reduce diabetic associated complications. Currently, available treatment is far from satisfactory and is expensive. Many indigenous Indian medicinal plants are successfully used to manage diabetes. Plant drugs are frequently considered to be less toxic and free from side effects than synthetic ones. However, the search for new antidiabetic drugs continues. Keeping this view, the present study aimed to evaluate the anti-diabetic Terminalia bellirica. Administration of Terminalia belliricato AXN rats restored the level of glucose profile. This confirms the antidiabetic activity of Terminalia bellirica. The potential antidiabetic activity of Terminalia belliricais due to the presence of phytochemical constitution present in the plant. Some of these phytochemicals such as Carbohydrates, Free amino acids, Alkaloids, Flavonoids, Tannins, Saponin, Quinones, Glycosides, Cardiac glycosides, Terpenoids, and polyphenolic compounds have possessed antidiabetic activity.