Design, Synthesis and Biological Activities of Novel Benzoyl Hydrazines Containing Pyrazole

被引：37

作者：

Yan Tao ^{[1
]}

Yu Shujing ^{[1
]}

Liu Pengfei ^{[1
]}

Liu Zhuo ^{[1
]}

Wang Baolei ^{[1
]}

Xiong Lixia ^{[1
]}

Li Zhengming ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab Elementoorgan Chem, Inst Elementoorgan Chem, Natl Pesticide Engn Res Ctr, Tianjin 300071, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2012年 / 30卷 / 04期

基金：

中国国家自然科学基金;

关键词：

benzoyl hydrazines; pyrazole; synthesis; insecticidal activities; fungicidal activities; HERBICIDAL ACTIVITY; DERIVATIVES; FLUBENDIAMIDE; INHIBITORS; ACID;

D O I：

10.1002/cjoc.201100347

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In search of environmentally benign compounds with high biological activity, low toxicity and low resistance, 8 novel benzoyl hydrazines containing pyrazole were designed and synthesized. All compounds were characterized by 1H NMR spectra and HRMS. The preliminary results of biological activity assessment indicated that most of title compounds exhibited certain insecticidal activities against Mythimna separata Walker at 200 mg center dot L-1 but excellent fungicidal activities against six fungus at 50 mg center dot L-1, which were better than the control.

引用

页码：919 / 923

页数：5

共 23 条

[1] Inhibitors of aspartic proteases - potential antimalarial agents [J].

Boss, C ;

Corminboeuf, O ;

Grisostomi, C ;

Weller, T .

EXPERT OPINION ON THERAPEUTIC PATENTS, 2006, 16 (03) :295-317

[2] Liquid chromatography-tandem mass spectrometric ion-switching determination of chlorantraniliprole and flubendiamide in fruits and vegetables [J].

Caboni, Pierluigi ;

Sarais, Giorgia ;

Angioni, Alberto ;

Vargiu, Simona ;

Pagnozzi, Daniela ;

Cabras, Paolo ;

Casida, John E. .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2008, 56 (17) :7696-7699

[3]

Cao J., 2007, FINE CHEM INTERMED, V37, P1

[4] THE FISCHER INDOLE SYNTHESIS .6. A NON-AROMATIC INTERMEDIATE AND A NEW CLASS OF HYDROINDOLES [J].

CARLIN, RB ;

CARLSON, DP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1959, 81 (17) :4673-4682

[5]

Chen N. C., 1991, BIOASSAY PESTICIDES, P161

[6] Synthesis, Structure and Biological Activities of Some Novel Anthranilic Acid Esters Containing N-Pyridylpyrazole [J].

Dong Weili ;

Xu Junying ;

Xiong Lixia ;

Liu Xinghai ;

Li Zhengming .

CHINESE JOURNAL OF CHEMISTRY, 2009, 27 (03) :579-586

[7]

Dong XL, 2011, CHINESE J ORG CHEM, V31, P1020

[8]

Fukuchi T., 2002, PCT Int. Appl. W.O. Patent, Patent No. [02,083,647, 02083647]

[9] Design, Synthesis, and 3D-QSAR Analysis of Novel 1,3,4-Oxadiazol-2(3H)-ones as Protoporphyrinogen Oxidase Inhibitors [J].

Jiang, Li-Li ;

Ying Tan ;

Zhu, Xiao-Lei ;

Wang, Zhi-Fang ;

Yang Zuo ;

Qiong Chen ;

Zhen Xi ;

Yang, Guang-Fu .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (05) :2643-2651

[10]

Ke SY, 2010, CHINESE J ORG CHEM, V30, P1820

← 1 2 3 →