Microwave-Assisted Synthesis and Spectral Properties of Some Benzoindohemicyanine and Benzoindodimethine Cyanine Dyes as well as the Interaction with Biomolecules

被引：5
|
作者：
Kang, Qiong [1 ]
Fan, Fangli [1 ]
Bi, Weibin [2 ]
Huang, Yi [3 ]
Fu, Yile [1 ]
Wang, Lanying [1 ]
机构：
[1] NW Univ Xian, Coll Chem & Mat Sci, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Peoples R China
[2] NW Univ Xian, Inst Condensed Matter Phys & Mat, Xian 710069, Peoples R China
[3] Xianyang Normal Univ, Dept Chem, Xianyang 712000, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 32卷 / 03期
关键词：
benzoindocyanine dye; microwave synthesis; spectral property; DNA; protein; HEMICYANINE DYES; DNA; ABSORPTION; SOLVATOCHROMISM; PHOTOSENSITIZER;
D O I：
10.6023/cjoc1107291
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two series of benzoindoeyanine dyes H1 similar to H4 and F1 similar to F4 were synthesized with the assistance of microwave irradiation under solvent-free condition using N-alkyl-2,3,3-trimethyl-4,5-benzoindole phosphate hexafluoropropylene and dimethylaminobenzaldehyde or indole-3-aldehyde as materials and piperidine as catalyst. All of the compounds were characterized by UV-Vis, H-1 NMR, IR techniques and elemental analysis. Their absorption spectral properities in different solvents were also investigated. The results showed that the lambda(max) of the dyes showed hypochromatic shifts with the increase of polarity in protic solvents, and bathochromic shifts with the decrease of polarity in aprotic solvents. The interactions of prepared dyes H3 and F2 with salmon sperm DNA, bovine serum albumin, muramidase, amylase and chymotrypsin were investigated, respectively. The results showed that the fluorescence intensity of H3 increased with the increase of DNA concentration.
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收藏
页码：567 / 573
页数：7
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