An intriguing case of a paravertebral extramedullary erythropoiesis presenting as tumor-mimicking lesion in a patient with eosinophilia with FIP1L1-PDGFRA rearrangement

被引:0
作者
Farah, Sassi [1 ,3 ]
Yoldez, Houcine [1 ]
Rahma, Ayadi [1 ]
Mona, Mlika [1 ]
Emna, Braham [1 ]
Mahdi, Abdennadher [2 ]
Faouzi, El Mezni [1 ]
机构
[1] Abderrahmen Mami Hosp, Pathol Dept, Ariana, Tunisia
[2] Abderrahmen Mami Hosp, Cardiovasc & Thorac Surg Dept, Ariana, Tunisia
[3] Abderrahmen Mami Hosp, Ariana 2080, Tunisia
关键词
eosinophilia; erythropoiesis; mediastinum; myeloproliferative neoplasm; tyrosine kinase inhibitor; MASS;
D O I
10.1002/ccr3.6637
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Extramedullary hematopoiesis in the posterior mediastinum is rare. Our case interested a 28-year-old man with a history of eosinophilia with FIP1L1-PDGFRA fusion gene who had a mediastinal mass surgically excised. Pathological examination concluded to an extramedullary erythropoiesis. This case is original by its location and the presence of only the erythroblastic line rearrangement.
引用
收藏
页数:5
相关论文
共 14 条
[1]   Intrathoracic extramedullary hematopoiesis presenting as tumor-simulating lesions of the mediastinum in α-thalassemia: A case report [J].
An, Jun ;
Weng, Yimin ;
He, Jinyuan ;
Li, Yun ;
Huang, Shaohong ;
Cai, Songwang ;
Zhang, Junhang .
ONCOLOGY LETTERS, 2015, 10 (04) :1993-1996
[2]  
Bain B.J., 2017, WHO WHO CLASSIFICATI, V4th, P54
[3]   Intrathoracic masses due to extramedullary hematopoiesis [J].
Castelli, R ;
Graziadei, G ;
Karimi, M ;
Cappellini, MD .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2004, 328 (05) :299-303
[4]   A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome [J].
Cools, J ;
DeAngelo, DJ ;
Gotlib, J ;
Stover, EH ;
Legare, RD ;
Cortes, J ;
Kutok, J ;
Clark, J ;
Galinsky, I ;
Griffin, JD ;
Cross, NCP ;
Tefferi, A ;
Malone, J ;
Alam, R ;
Schrier, SL ;
Schmid, J ;
Rose, M ;
Vandenberghe, P ;
Verhoef, G ;
Boogaerts, M ;
Wlodarska, I ;
Kantarjian, H ;
Marynen, P ;
Coutre, SE ;
Stone, R ;
Gilliland, DG .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (13) :1201-1214
[5]   Myeloid Neoplasm with PDGFRA Rearrangement Manifesting as a Retromolar Pad Mass [J].
Duffield, Amy S. ;
Webster, Jonathan ;
Smith, B. Douglas ;
Necciai, Julius S. ;
McCuiston, Austin ;
Ware, Alisha D. .
HEAD & NECK PATHOLOGY, 2021, 15 (04) :1399-1403
[6]   Myeloid neoplasm with eosinophilia associated with isolated extramedullary FIP1L1/PDGFR rearrangement [J].
Hilal, Talal ;
Fauble, Veena ;
Ketterling, Rhett P. ;
Kelemen, Katalin .
CANCER GENETICS, 2018, 220 :13-18
[7]  
Nguyen Giang Truong, 2019, Asian Cardiovasc Thorac Ann, V27, P135, DOI 10.1177/0218492318818966
[8]   Extramedullary haematopoiesis: radiological imaging features [J].
Roberts, A. S. ;
Shetty, A. S. ;
Mellnick, V. M. ;
Pickhardt, P. J. ;
Bhalla, S. ;
Menias, C. O. .
CLINICAL RADIOLOGY, 2016, 71 (09) :807-814
[9]   MR IMAGING OF INTRATHORACIC EXTRAMEDULLARY HEMATOPOIESIS [J].
SAVADER, SJ ;
OTERO, RR ;
SAVADER, BL .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1988, 12 (05) :878-880
[10]   EXTRAMEDULLARY ERYTHROPOIESIS IN HUMAN LIVER GRAFTS [J].
SCHLITT, HJ ;
SCHAFERS, S ;
DEIWICK, A ;
ECKARDT, KU ;
PIETSCH, T ;
EBELL, W ;
NASHAN, B ;
RINGE, B ;
WONIGEIT, K ;
PICHLMAYR, R .
HEPATOLOGY, 1995, 21 (03) :689-696