COVID-19 in older adults

被引:91
作者
Nanda, Aman [1 ]
Vura, Naga Venkata Rama Krishna [1 ]
Gravenstein, Stefan [1 ,2 ,3 ]
机构
[1] Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Div Geriatr & Palliat Med,Dept Med, 593 Eddy St,POB 438, Providence, RI 02903 USA
[2] Brown Univ, Sch Publ Hlth, Dept Hlth Serv Policy & Practice, Providence, RI 02912 USA
[3] Providence Vet Adm Med Ctr, Providence, RI 02908 USA
关键词
COVID-19; SARS-CoV-2; Elderly; Management; Transmission; Prevention; CORONAVIRUS; ACE2;
D O I
10.1007/s40520-020-01581-5
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
The advent of the SARS-CoV-2 and COVID-19 pandemic has generated a lot of publications at a rapid pace. We know that older adults disproportionately suffer the most severe of COVID outcomes. Here we attempt to coalesce the key knowledge of SARS-CoV-2 biology to the disease and clinical care concepts in the context of older adults.
引用
收藏
页码:1199 / 1202
页数:4
相关论文
共 16 条
[1]  
[Anonymous], 2020, Coronavirus Disease 2019
[2]   The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 [J].
Gorbalenya, Alexander E. ;
Baker, Susan C. ;
Baric, Ralph S. ;
de Groot, Raoul J. ;
Drosten, Christian ;
Gulyaeva, Anastasia A. ;
Haagmans, Bart L. ;
Lauber, Chris ;
Leontovich, Andrey M. ;
Neuman, Benjamin W. ;
Penzar, Dmitry ;
Perlman, Stanley ;
Poon, Leo L. M. ;
Samborskiy, Dmitry V. ;
Sidorov, Igor A. ;
Sola, Isabel ;
Ziebuhr, John .
NATURE MICROBIOLOGY, 2020, 5 (04) :536-544
[3]   Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis [J].
Hamming, I ;
Timens, W ;
Bulthuis, MLC ;
Lely, AT ;
Navis, GJ ;
van Goor, H .
JOURNAL OF PATHOLOGY, 2004, 203 (02) :631-637
[4]  
Hoffmann Markus, 2020, bioRxiv, DOI [10.1016/j.ebiom.2021.103255, 10.1101/2020.08.05.237651]
[5]   Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (vol 395, pg 497, 2020) [J].
Huang, C. ;
Wang, Y. ;
Li, X. .
LANCET, 2020, 395 (10223) :496-496
[6]  
Johns Hopkins University, 2020, COVID 19 MAP
[7]   The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application [J].
Lauer, Stephen A. ;
Grantz, Kyra H. ;
Bi, Qifang ;
Jones, Forrest K. ;
Zheng, Qulu ;
Meredith, Hannah R. ;
Azman, Andrew S. ;
Reich, Nicholas G. ;
Lessler, Justin .
ANNALS OF INTERNAL MEDICINE, 2020, 172 (09) :577-+
[8]   Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia [J].
Li, Qun ;
Guan, Xuhua ;
Wu, Peng ;
Wang, Xiaoye ;
Zhou, Lei ;
Tong, Yeqing ;
Ren, Ruiqi ;
Leung, Kathy S. M. ;
Lau, Eric H. Y. ;
Wong, Jessica Y. ;
Xing, Xuesen ;
Xiang, Nijuan ;
Wu, Yang ;
Li, Chao ;
Chen, Qi ;
Li, Dan ;
Liu, Tian ;
Zhao, Jing ;
Liu, Man ;
Tu, Wenxiao ;
Chen, Chuding ;
Jin, Lianmei ;
Yang, Rui ;
Wang, Qi ;
Zhou, Suhua ;
Wang, Rui ;
Liu, Hui ;
Luo, Yinbo ;
Liu, Yuan ;
Shao, Ge ;
Li, Huan ;
Tao, Zhongfa ;
Yang, Yang ;
Deng, Zhiqiang ;
Liu, Boxi ;
Ma, Zhitao ;
Zhang, Yanping ;
Shi, Guoqing ;
Lam, Tommy T. Y. ;
Wu, Joseph T. ;
Gao, George F. ;
Cowling, Benjamin J. ;
Yang, Bo ;
Leung, Gabriel M. ;
Feng, Zijian .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (13) :1199-1207
[9]   Obesity in Patients Younger Than 60 Years Is a Risk Factor for COVID-19 Hospital Admission [J].
Lighter, Jennifer ;
Phillips, Michael ;
Hochman, Sarah ;
Sterling, Stephanie ;
Johnson, Diane ;
Francois, Fritz ;
Stachel, Anna .
CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) :896-897
[10]   Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington [J].
McMichael, Temet M. ;
Currie, Dustin W. ;
Clark, Shauna ;
Pogosjans, Sargis ;
Kay, Meagan ;
Schwartz, Noah G. ;
Lewis, James ;
Baer, Atar ;
Kawakami, Vance ;
Lukoff, Margaret D. ;
Ferro, Jessica ;
Brostrom-Smith, Claire ;
Rea, Thomas D. ;
Sayre, Michael R. ;
Riedo, Francis X. ;
Russell, Denny ;
Hiatt, Brian ;
Montgomery, Patricia ;
Rao, Agam K. ;
Chow, Eric J. ;
Tobolowsky, Farrell ;
Hughes, Michael J. ;
Bardossy, Ana C. ;
Oakley, Lisa P. ;
Jacobs, Jesica R. ;
Stone, Nimalie D. ;
Reddy, Sujan C. ;
Jernigan, John A. ;
Honein, Margaret A. ;
Clark, Thomas A. ;
Duchin, Jeffrey S. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (21) :2005-2011