Telaprevir

被引:43
作者
Revill, P. [1 ]
Serradell, N. [1 ]
Bolos, J. [1 ]
Rosa, E. [1 ]
机构
[1] Prous Sci, Barcelona 08080, Spain
关键词
D O I
10.1358/dof.2007.032.09.1138229
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Telaprevir is an investigational oral hepatitis C virus (HCV) protease inhibitor in phase 11 evaluation in combination with pegylated interferon and ribavirin for the treatment of chronically infected patients wit genotype 1 hepatitis C. Interim results from a phase 11 trial indicated that this drug has the potential to shorten the duration of treatment for some patients with genotype 1 HCV. Additional phase 11 trials involve the treatment of patients who have failed previous interferon-based treatment, as well as treatment in the absence of ribavirin.
引用
收藏
页码:788 / 798
页数:11
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