Review article: monitoring of immunomodulators in inflammatory bowel disease

被引：53
作者：
Aberra, FN [1 ]
Lichtenstein, GR [1 ]
机构：
[1] Univ Penn, Hosp Univ Penn, Sch Med,Div Gastroenterol, Dept Med,Ctr Inflammatory Bowel Dis, Philadelphia, PA 19104 USA
来源：
ALIMENTARY PHARMACOLOGY & THERAPEUTICS | 2005年 / 21卷 / 04期
关键词：
D O I：
10.1111/j.1365-2036.2005.02343.x
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The armamentarium of medications for the treatment of inflammatory bowel disease is growing and becoming more complicated to use. Immunomodulators are a class of medications that have found a niche for the treatment of Crohn's disease and ulcerative colitis. Because of the mounting supporting evidence for efficacy, the most commonly-used immunomodulators are azathioprine, mercaptopurine, methotrexate and ciclosporin. These medications are being used more often due to their steroid-sparing and potentially surgery-sparing effects. Immunomodulators are also known for a significant side-effect profile and require careful monitoring. This review provides the latest information for clinicians on efficacy, side-effects, dosing and monitoring of these medications for treatment of inflammatory bowel disease.
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收藏
页码：307 / 319
页数：13
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