N-Heterocyclic carbene copper(I) complex-catalyzed synthesis of 2-aryl benzoxazoles and benzothiazoles

被引：43
|
作者：
Urzua, Julio I. [1 ]
Contreras, Renato [2 ]
Salas, Cristian O. [1 ]
Tapia, Ricardo A. [1 ]
机构：
[1] Pontificia Univ Catolica Chile, Fac Quim, Santiago 6094411, Chile
[2] Univ Chile, Fac Ciencias, Dept Quim, Casilla 653, Santiago, Chile
来源：
RSC ADVANCES | 2016年 / 6卷 / 85期
关键词：
INTRAMOLECULAR O-ARYLATION; ONE-POT SYNTHESIS; C-H BOND; CROSS-COUPLING REACTIONS; 2-SUBSTITUTED BENZOTHIAZOLES; CARBONYL-COMPOUNDS; DECARBOXYLATIVE ARYLATION; SUBSTITUTED BENZOXAZOLES; PALLADIUM COMPLEXES; ARYL CHLORIDES;
D O I：
10.1039/c6ra18510j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new and efficient synthesis of 2-arylbenzoxazoles and benzothiazoles using a copper N-heterocyclic carbene complex is described. In a simple protocol a variety of 2-substituted benzoxazoles and benzothiazoles were obtained via intramolecular coupling cyclization of 2-haloanilides/2-halothioanilides in good to excellent yields.
引用
收藏
页码：82401 / 82408
页数：8
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