Proximity aptasensor for protein detection based on an enzyme-free amplification strategy

被引：6
|
作者：
Yang, Dawei [1 ]
Tang, Yuguo [1 ]
Guo, Zhenzhen [1 ]
Chen, Xifeng [1 ,2 ]
Miao, Peng [1 ]
机构：
[1] Chinese Acad Sci, CAS Key Lab Biomed Diagnost, Suzhou Inst Biomed Engn & Technol, Suzhou 215163, Peoples R China
[2] Tianjin Guoke Jiaye Med Technol Dev Co Ltd, Tianjin 300399, Peoples R China
来源：
MOLECULAR BIOSYSTEMS | 2017年 / 13卷 / 10期
基金：
中国国家自然科学基金;
关键词：
HYBRIDIZATION CHAIN-REACTION; CYCLING SIGNAL AMPLIFICATION; DNA STRAND DISPLACEMENT; ELECTROCHEMICAL DETECTION; LIGATION ASSAYS; RELEASE SYSTEM; NUCLEIC-ACIDS; LABEL-FREE; IMMUNOASSAY; BIOMARKERS;
D O I：
10.1039/c7mb00458c
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel electrochemical aptasensor for the detection of trace protein is proposed based on proximity binding-induced strand displacement and hybridization chain reaction. This method is proven to be highly selective and has potential practical utility, and offers new opportunities for the convenient detection of proteins with an enzyme-free amplification process.
引用
收藏
页码：1936 / 1939
页数：4
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