Molecular analysis of the cholera toxin gene & antibiotic sensitivity profile of Vibrio cholerae O1 & O139 associated with mixed infection

被引：0
作者：
Sharma, C
Ghosh, A
Ghosh, RK
Mukhopadhyay, AK
Nair, GB
机构：
[1] Inst Microbial Technol, Chandigarh 160036, India
[2] Indian Inst Chem Biol, Calcutta 700032, W Bengal, India
[3] Natl Inst Cholera & Enter Dis, Calcutta, W Bengal, India
来源：
INDIAN JOURNAL OF MEDICAL RESEARCH | 1998年 / 107卷
关键词：
antibiotic sensitivity; co-infection; ribotype; toxin gene; Vibrio cholerae;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In the context of the reemergence of V. cholerae O1 in India and the recent evidence that O139 strains could have evolved from O1 E1 Tor strains, restriction fragment length polymorphism (RFLP) of the rRNA and the ctx genes and the antibiotic sensitivity profile of the two strains of V. cholerae, one an Oi and the other an O139, associated with mixed infection, were examined to determine their relatedness. Our results demonstrate that although the strains belonged to different. clones of V. cholerae, they showed similar antibiotic sensitivity profile indicating some exchange of genetic elements.
引用
收藏
页码：199 / 203
页数：5
相关论文
共 23 条
[1]   STRUCTURAL ORGANIZATION OF CHOLERA-TOXIN GENE AND ITS EXPRESSION IN AN ENVIRONMENTAL NONPATHOGENIC STRAIN OF VIBRIO-CHOLERAE [J].
BHATTACHARYYA, U ;
GHOSH, A ;
GHOSH, RK .
JOURNAL OF BIOSCIENCES, 1987, 11 (1-4) :231-238
[2]   COMPLETE NUCLEOTIDE-SEQUENCE OF A 23S RIBOSOMAL-RNA GENE FROM ESCHERICHIA-COLI [J].
BROSIUS, J ;
DULL, TJ ;
NOLLER, HF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (01) :201-204
[3]  
BROSIUS J, 1978, P NATL ACAD SCI USA, V75, P4801, DOI 10.1073/pnas.75.10.4801
[4]   CONSTRUCTION AND FINE MAPPING OF RECOMBINANT PLASMIDS CONTAINING THE RRNB RIBOSOMAL-RNA OPERON OF ESCHERICHIA-COLI [J].
BROSIUS, J ;
ULLRICH, A ;
RAKER, MA ;
GRAY, A ;
DULL, TJ ;
GUTELL, RR ;
NOLLER, HF .
PLASMID, 1981, 6 (01) :112-118
[5]   Changing epidemiology of cholera due to Vibrio cholerae O1 and O139 Bengal in Dhaka, Bangladesh [J].
Faruque, ASG ;
Fuchs, GJ ;
Albert, MJ .
EPIDEMIOLOGY AND INFECTION, 1996, 116 (03) :275-278
[6]   THE EXPRESSION OF BIOLOGICALLY-ACTIVE CHOLERA-TOXIN IN ESCHERICHIA-COLI [J].
GENNARO, ML ;
GREENAWAY, PJ ;
BROADBENT, DA .
NUCLEIC ACIDS RESEARCH, 1982, 10 (16) :4883-4890
[7]   VIBRIO-CHOLERAE NON-O1 SEROGROUP ASSOCIATED WITH CHOLERA GRAVIS GENETICALLY AND PHYSIOLOGICALLY RESEMBLES O1 EL-TOR CHOLERA STRAINS [J].
HALL, RH ;
KHAMBATY, FM ;
KOTHARY, MH ;
KEASLER, SP ;
TALL, BD .
INFECTION AND IMMUNITY, 1994, 62 (09) :3859-3863
[8]   REAPPEARANCE OF VIBRIO-CHOLERAE O1 AND CONCURRENT PREVALENCE OF O1 AND O139 IN VELLORE, SOUTH-INDIA [J].
JESUDASON, MV ;
SAMUEL, R ;
JOHN, TJ .
LANCET, 1994, 344 (8918) :335-336
[9]  
MATSEN JM, 1974, MANUAL CLIN MICROBIO, P418
[10]   DUPLICATION AND AMPLIFICATION OF TOXIN GENES IN VIBRIO-CHOLERAE [J].
MEKALANOS, JJ .
CELL, 1983, 35 (01) :253-263
123