Cancer-Targeted Nanotheranostics: Recent Advances and Perspectives

被引：171

作者：

Ma, Yufei ^{[1
]}

Huang, Jie ^{[1
]}

Song, Saijie ^{[1
]}

Chen, Huabing ^{[2
]}

Zhang, Zhijun ^{[1
]}

机构：

[1] Chinese Acad Sci, CAS Key Lab Nanobio Interface, Div Nanobiomed, CAS Ctr Excellence Nanosci,Suzhou Inst Nanotech &, Suzhou 215123, Peoples R China

[2] Soochow Univ, Coll Pharmaceut Sci, Jiangsu Key Lab Translat Res & Therapy Neuropsych, Suzhou 215123, Peoples R China

来源：

SMALL | 2016年 / 12卷 / 36期

关键词：

UP-CONVERSION NANOPARTICLES; IRON-OXIDE NANOPARTICLES; GUIDED DRUG-DELIVERY; MESOPOROUS SILICA NANOPARTICLES; PEGYLATED-LIPOSOMAL DOXORUBICIN; INFRARED PHOTOTHERMAL THERAPY; SOLID LIPID NANOPARTICLES; ONE-POT SYNTHESIS; MAGNETIC-RESONANCE; GRAPHENE OXIDE;

D O I：

10.1002/smll.201600635

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cancer-targeted nanotechnology is experiencing the trend of finding new materials with multiple functions for imaging and therapeutic applications. With the rapid development of the related fields, there exists a large number of reports regarding theranostic nanomedicine, decreasing the gap between cancer diagnosis and treatment with minimized separate comprehensions. In order to present an overview on the cancer-targeted nanotheranostics, we first describe their essential building blocks, including platforms, therapeutic agents and imaging agents, and then the recently rapidly developed multimodal theranostic systems. Finally we discuss the major challenges and the perspectives of future development of nanotheranostics toward clinical translations and personalized nanomedicine.

引用

页码：4936 / 4954

页数：19

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