A novel experimental procedure based on pure shear testing of dermatome-cut samples applied to porcine skin

被引:35
作者
Hollenstein, Marc [1 ]
Ehret, Alexander E. [2 ]
Itskov, Mikhail [2 ]
Mazza, Edoardo [1 ,3 ]
机构
[1] ETH, Inst Mech Syst, CH-8092 Zurich, Switzerland
[2] Rhein Westfal TH Aachen, Dept Continuum Mech, Aachen, Germany
[3] EMPA, CH-8600 Dubendorf, Switzerland
基金
瑞士国家科学基金会;
关键词
Pure shear; Soft tissue testing; Dermatome; Skin; Dermis; Anisotropy; Preconditioning; MECHANICAL-PROPERTIES; VISCOELASTIC PROPERTIES; IN-VIVO; MR ELASTOGRAPHY; BEHAVIOR; TISSUE; INDENTATION; COMPRESSION; LIVER;
D O I
10.1007/s10237-010-0263-1
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
This paper communicates a novel and robust method for the mechanical testing of thin layers of soft biological tissues with particular application to porcine skin. The key features include the use of a surgical dermatome and the highly defined deformation kinematics achieved by pure shear testing. Thin specimens of accurate thickness were prepared using a dermatome and were subjected to different quasi-static and dynamic loading protocols. Although simple in its experimental realisation, pure shear testing provides a number of advantages over other classic uni- and biaxial testing procedures. The preparation of thin specimens of porcine dermis, the mechanical tests as well as first representative results are described and discussed in detail. The results indicate a pronounced anisotropy between the directions along and across the cleavage lines and a strain rate-dependent response.
引用
收藏
页码:651 / 661
页数:11
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