Intramolecular Direct C-H Arylation via a Metallocenic Radical Pathway: Stereospecific Approach to Planar-Chiral Ferrocenes

被引：18

作者：

Liu, Yang

Xu, Jiancong

Zhang, Jinling

Xu, Xiaohua ^{[1
]}

Jin, Zhong ^{[1
]}

机构：

[1] Nankai Univ, Coll Chem, State Key Lab, Tianjin 300071, Peoples R China

来源：

ORGANIC LETTERS | 2017年 / 19卷 / 20期

基金：

中国国家自然科学基金;

关键词：

ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC CATALYSIS; COUPLING REACTIONS; ELECTRON-TRANSFER; CARBON-CARBON; ARYL HALIDES; LIGANDS; BUTOXIDE; PHENANTHRIDINONES; ORGANOCATALYST;

D O I：

10.1021/acs.orglett.7b02995

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Transition metal-free synthesis of planar-chiral 1,2-fused ferrocenes via intramolecular direct C-H bond arylation was achieved. The C-H arylation reactions promoted by a catalytic amount of 1,10-phenanthroline highlighted a unique planar-chiral metallocenic radical intermediate, generated from iodoferrocenes via a single-electron transfer process.

引用

收藏

页码：5709 / 5712

页数：4

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