Intramedullary PNET of the Spine: Long-term Survival After Combined Modality Therapy and Subsequent Relapse

被引：10

作者：

Gollard, Russell P. ^{[1
]}

Rosen, Larry ^{[2
]}

Anson, John ^{[3
]}

Mason, James ^{[5
]}

Khoury, Joe ^{[4
]}

机构：

[1] Canc & Blood Specialists Nevada, Henderson, NV 89074 USA

[2] Mike OCallaghan Fed Hosp, Nellis AFB, NV USA

[3] Western Reg Ctr Brain & Spinal Surg, Las Vegas, NV USA

[4] Nevada Canc Inst, Las Vegas, NV USA

[5] Scripps Clin, La Jolla, CA USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2011年 / 33卷 / 02期

关键词：

neuroectodermal tumors; neoplasm of spine; pediatric medulloblastoma protocol; PRIMITIVE NEUROECTODERMAL TUMOR; OF-THE-LITERATURE; CORD; MEDULLOBLASTOMA; TRANSPLANTATION; CLASSIFICATION; CHEMOTHERAPY;

D O I：

10.1097/MPH.0b013e3181f84b7f

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Primitive neuroectodermal tumors (PNET) originating within the spinal cord are extraordinarily rare. We report a female who presented at age 21 with diffuse involvement of the lower spinal cord. After biopsy and successful treatment with radiation and chemotherapy, she recurred 10 years later with disease in her cerebellum. She was reinduced with chemotherapy and subsequently received high-dose chemotherapy with autologous stem cell support. She is alive and free of disease 11 years after her initial presentation. This represents the longest survival ever documented for a primary spinal PNET.

引用

页码：107 / 112

页数：6

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