When Should F-18 FDG PET/CT Be Used Instead of 68Ga-DOTA-Peptides to Investigate Metastatic Neuroendocrine Tumors?

被引：5

作者：

Fuccio, Chiara ^{[4
]}

Musto, Alessandra ^{[2
,3
]}

Cambioli, Silvia ^{[4
]}

Castellucci, Paolo ^{[4
]}

Pantaleo, Maria A. ^{[5
]}

Nanni, Cristina ^{[4
]}

Montini, Gian C. ^{[4
]}

Campana, Davide ^{[6
]}

Tomassetti, Paolo ^{[6
]}

Bellan, Elena ^{[2
,3
]}

Massaro, Arianna ^{[2
,3
]}

Grassetto, Gaia ^{[2
,3
]}

Rubello, Domenico ^{[1
,2
,3
]}

Fanti, Stefano ^{[4
]}

机构：

[1] Santa Maria della Misericordia Hosp, Dept Nucl Med, PET Ctr, I-45100 Rovigo, Italy

[2] Santa Maria della Misericordia Hosp, Dept Med Phys, I-45100 Rovigo, Italy

[3] Santa Maria della Misericordia Hosp, Dept Radiol, I-45100 Rovigo, Italy

[4] S Orsola Malpighi Univ Hosp, Azienda Osped Univ Bologna, Dept Nucl Med, Bologna, Italy

[5] S Orsola Malpighi Univ Hosp, Azienda Osped Univ Bologna, Dept Oncol, Bologna, Italy

[6] S Orsola Malpighi Univ Hosp, Azienda Osped Univ Bologna, Dept Internal Med, Bologna, Italy

来源：

CLINICAL NUCLEAR MEDICINE | 2011年 / 36卷 / 12期

关键词：

aggressive NETs; PET/CT; F-18; FDG; Ga-68-DOTA-NOC; management; POSITRON-EMISSION-TOMOGRAPHY; Y-90-DOTATOC THERAPY; PHARMACOKINETICS; GA-68-DOTATOC;

D O I：

10.1097/RLU.0b013e31823361f7

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 67-year-old man, previously operated for a pancreatic neuroendocrine tumor (NET), had progressive increase of serum chromogranin A during follow-up. Sequential Ga-68-DOTA-NOC and F-18 FDG PET/CT were performed. Ga-68-DOTA-NOC imaging was negative, whereas F-18 FDG PET/CT showed 2 hypermetabolic hepatic lesions demonstrated at CT-guided biopsy as metastatic deposits from a high-grade (G3) aggressive NET. Despite the large consensus of SPECT or PET with radiolabeled somatostatin analogs as first choice in functional imaging for detecting NETs metastasis, F-18 FDG may occasionally be the right tracer to provide accurate diagnostic and prognostic information in aggressive G3 NET.

引用

页码：1109 / 1111

页数：3

共 8 条

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