Management of central nervous system relapse in a young patient affected by primary mediastinal large B-cell lymphoma: A case report

被引:3
作者
Marangon, Miriam [1 ]
Casadei, Beatrice [1 ]
Broccoli, Alessandro [1 ]
Argnani, Lisa [1 ]
Cavo, Michele [1 ]
Zinzani, Pier Luigi [1 ]
机构
[1] Univ Bologna, Inst Hematol L&A Seragnoli, Via Massarenti 9, I-40138 Bologna, Italy
关键词
autologous stem cell transplant; central nervous system involvement; MATRix regimen; primary mediastinal large B-cell lymphoma; INTERNATIONAL EXTRANODAL LYMPHOMA; RISK-FACTORS; CNS RELAPSE; RITUXIMAB; CHEMOIMMUNOTHERAPY; RANDOMIZATION; METHOTREXATE; PROPHYLAXIS; EXPERIENCE; IMPACT;
D O I
10.1002/ccr3.2706
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In primary mediastinal large B-cell lymphoma, central nervous system (CNS) relapse is an uncommon event with a dismal prognosis. We report about the successful management of CNS relapse with chemoimmunotherapy according to MATRix (methotrexate, cytarabine, thiotepa, and rituximab) protocol followed by autologous stem cell transplant.
引用
收藏
页码:933 / 937
页数:5
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