Exceptional Response on Addition of Everolimus to Taxane in Urothelial Carcinoma Bearing an NF2 Mutation

被引:23
作者
Ali, Siraj M. [1 ]
Miller, Vincent A. [1 ]
Ross, Jeffrey S. [1 ]
Pal, Sumanta K. [2 ]
机构
[1] Fdn Med, Cambridge, MA USA
[2] City Hope Comprehens Canc Ctr, Dept Med Oncol & Expt Therapeut, Duarte, CA 91010 USA
关键词
D O I
10.1016/j.eururo.2015.01.015
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1195 / 1196
页数:3
相关论文
共 4 条
[1]   Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing [J].
Frampton, Garrett M. ;
Fichtenholtz, Alex ;
Otto, Geoff A. ;
Wang, Kai ;
Downing, Sean R. ;
He, Jie ;
Schnall-Levin, Michael ;
White, Jared ;
Sanford, Eric M. ;
An, Peter ;
Sun, James ;
Juhn, Frank ;
Brennan, Kristina ;
Iwanik, Kiel ;
Maillet, Ashley ;
Buell, Jamie ;
White, Emily ;
Zhao, Mandy ;
Balasubramanian, Sohail ;
Terzic, Selmira ;
Richards, Tina ;
Banning, Vera ;
Garcia, Lazaro ;
Mahoney, Kristen ;
Zwirko, Zac ;
Donahue, Amy ;
Beltran, Himisha ;
Mosquera, Juan Miguel ;
Rubin, Mark A. ;
Dogan, Snjezana ;
Hedvat, Cyrus V. ;
Berger, Michael F. ;
Pusztai, Lajos ;
Lechner, Matthias ;
Boshoff, Chris ;
Jarosz, Mirna ;
Vietz, Christine ;
Parker, Alex ;
Miller, Vincent A. ;
Ross, Jeffrey S. ;
Curran, John ;
Cronin, Maureen T. ;
Stephens, Philip J. ;
Lipson, Doron ;
Yelensky, Roman .
NATURE BIOTECHNOLOGY, 2013, 31 (11) :1023-+
[2]   Genome Sequencing Identifies a Basis for Everolimus Sensitivity [J].
Iyer, Gopa ;
Hanrahan, Aphrothiti J. ;
Milowsky, Matthew I. ;
Al-Ahmadie, Hikmat ;
Scott, Sasinya N. ;
Janakiraman, Manickam ;
Pirun, Mono ;
Sander, Chris ;
Socci, Nicholas D. ;
Ostrovnaya, Irina ;
Viale, Agnes ;
Heguy, Adriana ;
Peng, Luke ;
Chan, Timothy A. ;
Bochner, Bernard ;
Bajorin, Dean F. ;
Berger, Michael F. ;
Taylor, Barry S. ;
Solit, David B. .
SCIENCE, 2012, 338 (6104) :221-221
[3]   Second-line systemic therapy and emerging drugs for metastatic transitional-cell carcinoma of the urothelium [J].
Sonpavde, Guru ;
Sternberg, Cora N. ;
Rosenberg, Jonathan E. ;
Hahn, Noah M. ;
Galsky, Matthew D. ;
Vogelzang, Nicholas J. .
LANCET ONCOLOGY, 2010, 11 (09) :861-870
[4]   Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib [J].
Wagle, Nikhil ;
Grabiner, Brian C. ;
Van Allen, Eliezer M. ;
Hodis, Eran ;
Jacobus, Susanna ;
Supko, Jeffrey G. ;
Stewart, Michelle ;
Choueiri, Toni K. ;
Gandhi, Leena ;
Cleary, James M. ;
Elfiky, Aymen A. ;
Taplin, Mary Ellen ;
Stack, Edward C. ;
Signoretti, Sabina ;
Loda, Massimo ;
Shapiro, Geoffrey I. ;
Sabatini, David M. ;
Lander, Eric S. ;
Gabriel, Stacey B. ;
Kantoff, Philip W. ;
Garraway, Levi A. ;
Rosenberg, Jonathan E. .
CANCER DISCOVERY, 2014, 4 (05) :546-553