Imperative partial nephrectomy for renal cell carcinoma: Oncological and functional results

被引：1

作者：

Lecouteux, A. ^{[1
]}

Rigaud, J. ^{[1
]}

Glemain, P. ^{[1
]}

Le Normand, L. ^{[1
]}

Bouchot, O. ^{[1
]}

Karam, G. ^{[1
]}

机构：

[1] CHU Nantes, Urol Clin, F-44093 Nantes 01, France

来源：

PROGRES EN UROLOGIE | 2011年 / 21卷 / 09期

关键词：

Kidney; Nephron sparing surgery; Imperative indication; Renal cell carcinoma; NEPHRON-SPARING SURGERY; SOLITARY KIDNEY; TUMOR; COMPLICATIONS; MORBIDITY; OUTCOMES; DISEASE; CM;

D O I：

10.1016/j.purol.2011.04.009

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives. - To study oncological results and functional results after partial nephrectomy in imperative indication for the treatment of renal cell carcinoma. Patients and methods. - From January 1990 to December 2009, 65 partial nephrectomies in 61 patients were performed in imperative indication for renal cell carcinoma. Results. - The mean age of patients was 59.3 years. The mean follow-up was 47.4 months. The tumours were asymptomatic in 87.5%. The average tumour diameter was 4.3 cm. Twenty-nine percent of patients relapsed after a mean time of 27.4 months. The morbidity was 38.5%. Preoperative and endpoint serum creatinine and renal clearance were respectively 119 mu mol/L and 63.1 mL/min versus 137 mu mol/L and 50.9 mL/min (P=0.0003; 0.0002). Overall survival at one, three, five and ten years was 98.4%, 91.2%, 91.2% and 51.9%. Conclusion. - Partial nephrectomy in imperative indication for renal cell carcinoma has helped preserve renal function but has a significant morbidity and recurrence rate. (C) 2011 Elsevier Masson SAS. All rights reserved.

引用

页码：599 / 606

页数：8

共 20 条

[1] Excellent long-term cancer control with elective nephron-sparing surgery for selected renal cell carcinomas measuring more than 4 cm [J].