BTK Leu528Trp-a Potential Secondary Resistance Mechanism Specific for Patients with Chronic Lymphocytic Leukemia Treated with the Next Generation BTK Inhibitor Zanubrutinib

被引：50

作者：

Handunnetti, Sasanka M. ^{[1
,2
,3
]}

Tang, Chloe Pek Sang ^{[4
]}

Tamia Nguyen ^{[1
]}

Zhou, Xing ^{[5
]}

Thompson, Ella ^{[1
,2
]}

Sun, Hanzi ^{[5
]}

Xing, Haimei ^{[5
]}

Zhang, Bo ^{[5
]}

Guo, Yin ^{[5
]}

Sutton, Lesley Ann ^{[6
]}

Ghia, Paolo ^{[7
,8
]}

Rosenquist, Richard ^{[6
]}

Scarfo, Lydia ^{[7
,8
]}

Bonfiglio, Silvia ^{[7
,8
]}

Seymour, John F. ^{[1
,3
]}

Anderson, Mary Ann ^{[1
,3
]}

Roberts, Andrew W. ^{[1
,3
,9
]}

Huang, David C. S. ^{[2
,9
]}

Liu, Ye ^{[5
]}

Cheah, Chan Y. ^{[10
,11
]}

Westerman, David Alan ^{[1
,3
]}

Yeh, Paul Sung-Hao ^{[1
]}

Tam, Constantine S. ^{[1
,2
,4
]}

Blombery, Piers ^{[1
,2
,3
]}

机构：

[1] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

[2] Univ Melbourne, Melbourne, Vic, Australia

[3] Royal Melbourne Hosp, Melbourne, Vic, Australia

[4] St Vincents Hosp Melbourne, Melbourne, Vic, Australia

[5] Beigene, Beijing, Peoples R China

[6] Karolinska Inst, Stockholm, Sweden

[7] Univ Vita Salute San Raffaele, Milan, Italy

[8] IRCCS Osped San Raffaele, Milan, Italy

[9] Walter & Eliza Hall Inst Med Res, Melbourne, Vic, Australia

[10] Univ Western Australia, Sch Med, Perth, WA, Australia

[11] Sir Charles Gairdner Hosp, Dept Haematol, Perth, WA, Australia

来源：

BLOOD | 2019年 / 134卷

关键词：

D O I：

10.1182/blood-2019-125488

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

170

引用

页数：5