Treatment options for methicillin-resistant Staphylococcus aureus (MRSA) infection: Where are we now?

被引：18
作者：
Edwards, B. [1 ]
Andini, R. [2 ]
Esposito, S. [3 ]
Grossi, P. [4 ]
Lew, D. [5 ]
Mazzei, T. [6 ]
Novelli, A. [6 ]
Soriano, A. [7 ]
Gould, I. M. [8 ]
机构：
[1] Royal Infirm Edinburgh NHS Trust, Dept Med Microbiol, Edinburgh EH16 4SA, Midlothian, Scotland
[2] Univ Naples 2, AORN Monaldi, UOC Transplant & Infect Dis Med, Naples, Italy
[3] Univ Salerno, Dept Med, I-84100 Salerno, Italy
[4] Univ Unisubria, Dept Surg & Morphol Studies, Varese, Italy
[5] Univ Hosp Geneva, Chief Dept Specialties Internal Med, Chief Infect Dis Div, Geneva, Switzerland
[6] Univ Florence, Dept Hlth Sci, Clin Pharmacol & Oncol Sect, Florence, Italy
[7] Hosp Clin Barcelona, IDIBAPS, Dept Infect Dis, Barcelona, Spain
[8] Aberdeen Royal Infirm, Dept Med Microbiol, Aberdeen, Scotland
来源：
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE | 2014年 / 2卷 / 03期
关键词：
MRSA; Treatment; Susceptibility testing; MINIMUM INHIBITORY CONCENTRATION; HIGH-DOSE DAPTOMYCIN; BLOOD-STREAM INFECTIONS; LINEZOLID-ASSOCIATED THROMBOCYTOPENIA; CONTINUOUS VENOVENOUS HEMOFILTRATION; VANCOMYCIN-INTERMEDIATE RESISTANCE; CRITICALLY-ILL PATIENTS; SOFT-TISSUE INFECTIONS; CONTINUOUS-INFUSION; EXPERIMENTAL ENDOCARDITIS;
D O I：
10.1016/j.jgar.2014.03.009
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Methicillin-resistant Staphylococcus aureus (MRSA) infection continues to be a substantial global problem with significant associated morbidity and mortality. This review summarises the discussions that took place at the 4th MRSA Consensus Conference in relation to the current treatment options for serious MRSA infections and how to optimise whichever therapy is embarked upon. It highlights the many challenges faced by both the laboratory and clinicians in the diagnosis and treatment of MRSA infections. (C) 2014 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.
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收藏
页码：133 / 140
页数：8
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