Hydrosalpinx and infertility: what about conservative surgical management?

被引:28
作者
Chanelles, Olivier [1 ,4 ]
Ducarme, Guillaume [1 ,4 ]
Sifer, Christophe [2 ,4 ]
Hugues, Jean-Noel [3 ,4 ]
Touboul, Cyril [1 ,4 ]
Poncelet, Christophe [1 ,4 ]
机构
[1] Jean Verdier Hosp, AP HP, Dept Obstet & Gynecol, F-93143 Bondy, France
[2] Jean Verdier Hosp, AP HP, Dept Reprod Biol, F-93143 Bondy, France
[3] Jean Verdier Hosp, AP HP, Dept Reprod Med, F-93143 Bondy, France
[4] Univ Paris 13, Bobigny, France
关键词
Hydrosalpinx; Neosalpingostomy; Salpingectomy; IVF; Infertility; IN-VITRO FERTILIZATION; RIGHT UPPER QUADRANT; PREGNANCY RATES; UNILATERAL HYDROSALPINX; TUBAL PATHOLOGY; EMBRYO-TRANSFER; POSTAL SURVEY; SALPINGECTOMY; IVF; HYSTEROSALPINGOGRAPHY;
D O I
10.1016/j.ejogrb.2011.07.004
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: The aim of this study was to assess and validate a management protocol for infertile patients affected by at least one hydrosalpinx. Study design: Eighty-one consecutive infertile normo-ovulatory patients with uni or bilateral hydrosalpinx planed to be surgically managed were included in the protocol from November 2003 to May 2007. During laparoscopy, a systematic evaluation of the tubes was firstly conducted and the local management protocol based on validated tubal prognostic scores was applied. Surgery for hydrosalpinx was either conservative by neosalpingostomy or radical by salpingectomy. The primary end-point was the cumulative clinical pregnancy rate. Results: 115 hydrosalpinges out of 153 present tubes were confirmed during laparoscopy. Neosalpingostomy was possible in 35 patients featuring 50 hydrosalpinges (43.2% and 43.5%, respectively). Salpingectomy was necessary for the others (46 patients representing 65 hydrosalpinges). The mean follow-up period was 31.8 +/- 12.4 months. The overall cumulative pregnancy rate was 61% per couple who completed the protocol (33/54 patients). The cumulative pregnancy rate was 50% after IVF in patients who underwent bilateral salpingectomy. Among patients with at least one functional tube, the overall cumulative pregnancy rate was 633%, with a spontaneous pregnancy rate of 30.4%. Conclusion: Hydrosalpinx management can be conservative with a tubal conservative of 43.5% and fair chances for spontaneous conception. An integrated management of hydrosalpinx including ART actually leads to a cumulative pregnancy rate of 61% per patient. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:122 / 126
页数:5
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