Clinical features of children with both ADHD and mania: does ascertainment source make a difference?

被引：44
作者：
Biederman, J
Russell, R
Soriano, J
Wozniak, J
Faraone, SV
机构：
[1] Massachusetts Gen Hosp, Child Psychiat Serv, Pediat Psychopharmacol Unit, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Massachusetts Mental Hlth Ctr,Dept Psychiat, Harvard Inst Psychiat Epidemiol & Genet, Boston, MA 02115 USA
[3] Commonwealth Res Ctr, Boston, MA USA
来源：
JOURNAL OF AFFECTIVE DISORDERS | 1998年 / 51卷 / 02期
关键词：
bipolar disorder; ADHD; comorbidity; children; adolescents;
D O I：
10.1016/S0165-0327(98)00177-3
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Objective: We evaluated the structural diagnostic results of children ascertained through an ADHD diagnosis with comorbid mania to determine if they have the same phenotype as children ascertained through a mania diagnosis with comorbid ADHD. Method: We compared a sample of children participating in a family genetic study of ADHD to a sample of children ascertained through a study of childhood mania. Results: Similar correlates of ADHD and mania were observed in children satisfying criteria for both disorders irrespective of ascertainment source. Conclusions: Findings suggest that children with mania and ADHD have two disorders, their features not varying with the primary diagnostic focus. Limitations: The results may have been limited by small sample size. Clinical relevance: Because the coexistence of ADHD and mania seriously complicates the course and treatment of children, understanding the compatibility of these disorders has important clinical implications in the management of this population. (C) 1998 Elsevier Science B.V. All rights reserved.
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收藏
页码：101 / 112
页数：12
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