Bisphosphonate Therapy is Effective in the Treatment of Sacral Giant Cell Tumor

被引：16

作者：

Chaudhary, Preeti ^{[1
]}

Khadim, Haider ^{[2
]}

Gajra, Ajeet ^{[2
]}

Damron, Timothy ^{[3
]}

Shah, Chirag ^{[2
]}

机构：

[1] SUNY Upstate Med Ctr, Dept Internal Med, Syracuse, NY USA

[2] SUNY Upstate Med Ctr, Dept Hematol Oncol, Syracuse, NY USA

[3] SUNY Upstate Med Univ, Dept Orthoped, Upstate Bone & Joint Ctr, E Syracuse, NY USA

来源：

ONKOLOGIE | 2011年 / 34卷 / 12期

关键词：

Giant cell tumor; Sacral; Bisphosphonates; RECURRENCE; BONE;

D O I：

10.1159/000334549

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Sacral giant cell tumors are particularly challenging to treat as they are often quite extensive and surround the sacral nerve roots, making surgical extirpation very difficult without high morbidity and frequent local recurrence. Case Report: We report on a 33-year-old male patient with sacral giant cell tumor treated with intravenous bisphosphonate therapy after early failure of embolization procedures. At 3 years follow-up, the patient had no pain, no neurological deficits, and no local recurrence. Conclusion: To our knowledge, this is one of the first reported cases of bisphosphonate therapy after failed embolization for control of a difficult giant cell tumor.

引用

页码：702 / 704

页数：3

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