Long-Term Follow-Up After Laparoscopic Management of Endometrial Cancer in the Obese: A Fifteen-Year Cohort Study

被引：23

作者：

Rabischong, Benoit ^{[1
]}

Larrain, Demetrio ^{[1
]}

Canis, Michel ^{[1
]}

Le Bouedec, Guillaume ^{[2
]}

Pomel, Christophe ^{[2
]}

Jardon, Kris ^{[1
]}

Kwiatkowski, Fabrice ^{[3
]}

Bourdel, Nicolas ^{[1
]}

Achard, Jean-Louis ^{[2
]}

Dauplat, Jacques ^{[2
]}

Mage, Gerard ^{[1
]}

机构：

[1] Univ Auvergne, CHU Estaing, CHU Clermont Ferrand, Dept Obstet Gynecol & Human Reprod, Clermont Ferrand, France

[2] Jean Perrin Canc Ctr, Dept Gynecol Oncol & Surg, Clermont Ferrand, France

[3] Jean Perrin Canc Ctr, Dept Med Res & Biostat, Clermont Ferrand, France

来源：

JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY | 2011年 / 18卷 / 05期

关键词：

Laparoscopy; Endometrial cancer; Obesity; Long-term follow-up; Survival; BODY-MASS-INDEX; ASSISTED VAGINAL HYSTERECTOMY; ABDOMINAL HYSTERECTOMY; SURGICAL OUTCOMES; FROZEN-SECTION; WOMEN; SURGERY; LYMPHADENECTOMY; OVERWEIGHT; CARCINOMA;

D O I：

10.1016/j.jmig.2011.05.015

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Study Objective: To assess the surgical outcomes and long-term results of laparoscopic treatment of endometrial cancer in obese patients, and compare these results with those of nonobese women. Design: Retrospective cohort study (Canadian Task Force classification II-2). Setting: Two referral cancer centers. Patients: Fifty-two obese and 155 nonobese women with clinical stage I endometrial cancer managed by laparoscopy from 1990-2005 in two referral centers. Interventions: Demographic, surgical, perioperative and pathological characteristics of obese women and nonobese women with endometrial cancer treated by laparoscopy were analyzed and then compared. Recurrence-free and overall survival was calculated by use of Kaplan-Meier method. Measurements and Main Results: Median BMI of the study population was 26.2 Kg/m(2). Median BMI among obese patients was 34.2 Kg/m(2). The conversion rate was independent from the BMI of the patient (3.8% vs 4.5%, p =.80). Neither mean operative time (187.5 vs 172 min, p = .11) neither hospital stay (5.2 vs 4.9 days, p = .44) were related with BMI. Lymphadenectomy was considered not feasible in 7 obese (17%) and 8 nonobese (7%) women (p = 0.09). Fewer lymph nodes were retrieved among obese women (8 versus II, p <.0002). No differences were found between the groups in terms of perioperative complications. Median follow-up was 69 and 71 months for the obese and nonobese, respectively (p = .59). Overall and disease-free 5-year survival rates did not differ between obese and nonobese patients (90.3% and 87.5% versus 88.5% and 89.8%, respectively). Conclusion: Despite some limitations, the laparoscopic approach seems to be particularly useful for obese patients with endometrial cancer, with similar survival and recurrence rates and without any more complications compared to the nonobese population. Journal of Minimally Invasive Gynecology (2011) 18, 589-596 (C) 2011 AAGL. All rights reserved.

引用

页码：589 / 596

页数：8

共 60 条

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