Obesity and Thyroid Cancer Risk: An Update

被引：73

作者：

Franchini, Fabiana ^{[1
]}

Palatucci, Giuseppe ^{[1
]}

Colao, Annamaria ^{[1
]}

Ungaro, Paola ^{[2
]}

Macchia, Paolo Emidio ^{[1
]}

Nettore, Immacolata Cristina ^{[1
]}

机构：

[1] Univ Naples Federico II, Dept Clin Med & Surg, I-80131 Naples, Italy

[2] CNR, Inst Expt Endocrinol & Oncol Gaetano Salvatore, I-80145 Naples, Italy

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2022年 / 19卷 / 03期

关键词：

thyroid carcinoma; obesity; overweight; risk factors; cytokines; insulin; insulin resistance; estrogens; oxidative stress; BODY-MASS INDEX; INSULIN-RESISTANCE; ADIPONECTIN RECEPTORS; DECREASED EXPRESSION; ESTROGEN-RECEPTORS; OXIDATIVE STRESS; ADIPOSE-TISSUE; MESSENGER-RNA; UNITED-STATES; FREE-RADICALS;

D O I：

10.3390/ijerph19031116

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Thyroid cancer (TC) is the most common endocrine malignancy worldwide and its incidence has increased dramatically in recent years. In parallel, the prevalence of overweight and obesity has also increased, suggesting a possible link between these two diseases. Indeed, low-grade chronic inflammation, altered cytokine levels, insulin resistance, oxidative stress, and hormonal changes that occur in obese patients are all factors that contribute to the occurrence and growth of TC. In this review, the most recent evidence supporting the potential role of the mechanisms linking obesity to TC will be discussed.

引用

页数：15

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