Hybrid Plasmonic SOI Ring Resonator for Bulk and Affinity Bio - sensing Applications

被引:16
作者
Kumari, Soumya [1 ]
Tripathi, Saurabh Mani [1 ,2 ]
机构
[1] Indian Inst Technol Kanpur, Ctr Lasers & Photon Dept, Kanpur 208016, Uttar Pradesh, India
[2] Indian Inst Technol Kanpur, Dept Phys, Kanpur 208016, Uttar Pradesh, India
关键词
Ring resonator; Hybrid Plasmonic waveguide; Bulk refractive index biosensor; Affinity biosensor; beta-Lactoglobulin molecules; Affinity sensitivity; Silicon-on-insulator; REFRACTIVE-INDEX; LACTOGLOBULIN; BIOSENSORS;
D O I
10.1007/s12633-022-01877-3
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We study a SOI hybrid plasmonic waveguide (Silicon - slot - metal) micro-ring resonator for bulk and affinity sensing applications. The opto-geometric parameters of the sensors have been optimized to enhance the affinity sensitivity by maximizing the modal field confinement in the sensing (slot) region. Keeping the practicality aspect in view, we have performed the simulations by considering a specific case of beta-Lactoglobulin protein molecules in liquid phase as an example. The maximum attained bulk refractive index sensitivity is 555 nm/RIU with a figure of merit of 154.16 RIU-1 when 10% beta-Lactoglobulin molecules are present in the sample. A more realistic approach has been proposed for investigation of affinity sensing with the results further compared to the existing approach. Effect of varied thickness of biomolecule adlayer in the slot region, in which the modal electric field is immensely confined, has been studied. We observe that with increasing adlayer thickness, the surface sensitivity increases exponentially and a very high affinity sensitivity of 0.97 nm/nm has been observed when the biomolecules are immobilized over the entire slot region. Our study may find direct application in quantitative detection of beta-Lactoglobulin protein molecules in bio-sample, and in designing highly sensitive photonic biosensors for specific detection of biomolecules by incorporating appropriate immobilization schemes.
引用
收藏
页码:11577 / 11586
页数:10
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