Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States

被引:932
作者
Patel, T [1 ]
机构
[1] Texas A&M Univ Syst, Hlth Sci Ctr, Coll Med, Scott & White Clin,Div Gastroenterol, Temple, TX 76508 USA
关键词
D O I
10.1053/jhep.2001.25087
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Clinical observations suggest a recent increase in intrahepatic biliary tract malignancies, Thus, our aim was to determine recent trends in the epidemiology of intrahepatic cholangiocarcinoma in the United States, Reported data from the Surveillance, Epidemiology, and End Results (SEER) program and the United States Vital Statistics databases were analyzed to determine the incidence, mortality, and survival rates of primary intrahepatic cholangiocarcinoma. Between 1973 and 1997, the incidence and mortality rates from intrahepatic cholangiocarcinoma markedly increased, with an estimated annual percent change (EAPC) of 9.11% (95% CI, 7.46 to 10.78) and 9.44% (95%, CI 8.46 to 10.41), respectively. The age-adjusted mortality rate per 100,000 persons for whites increased from 0.14 for the period 1975-1979 to 0.65 for the period 1993-1997, and that for blacks increased from 0.15 to 0.58 over the same period, The increase in mortality was similar across all age groups above age 45, The relative 1- and 2-year survival rates following diagnosis from 1989 to 1996 were 24.5% and 12.8%, respectively, In conclusion, there has been a marked increase in the incidence and mortality from intrahepatic cholangiocarcinoma in the United States in recent years. This tumor continues to be associated with a poor prognosis.
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页码:1353 / 1357
页数:5
相关论文
共 34 条
  • [1] Medical progress - Biliary tract cancers
    de Groen, PC
    Gores, GJ
    LaRusso, NF
    Gunderson, LL
    Nagorney, DM
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (18) : 1368 - 1378
  • [2] Department of Health and Human Services, 1989, ICD9CM DEP HLTH HUM
  • [3] Devesa SS., 1999, ATLAS CANC MORTALITY
  • [4] Rising incidence of hepatocellular carcinoma in the United States
    El-Serag, HB
    Mason, AC
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (10) : 745 - 750
  • [6] GORDON FD, 1996, LIVER BILIARY DIS, P755
  • [7] A 3-year prospective study on serum tumor markers used for detecting cholangiocarcinoma in patients with primary sclerosing cholangitis
    Hultcrantz, R
    Olsson, R
    Danielsson, B
    Järnerot, C
    Lööf, L
    Ryden, BO
    Wahren, B
    Broomé, U
    [J]. JOURNAL OF HEPATOLOGY, 1999, 30 (04) : 669 - 673
  • [8] Jones B A, 1998, Clin Liver Dis, V2, P437, DOI 10.1016/S1089-3261(05)70017-9
  • [9] KATO I, 1990, JPN J CLIN ONCOL, V20, P232
  • [10] Kazerouni N, 2000, AM J IND MED, V38, P410, DOI 10.1002/1097-0274(200010)38:4<410::AID-AJIM6>3.0.CO