Functional, Genetic and Biochemical Biomarkers of Peripheral Arterial Disease

被引：2

作者：

Charakida, M. ^{[1
]}

Masi, S. ^{[1
]}

Tousoulis, D. ^{[2
]}

机构：

[1] UCL, Inst Child Hlth, Vasc Physiol Unit, London WC1EJH, England

[2] Hippokrateion Hosp, Dept Cardiol 1, Athens, Greece

来源：

CURRENT MEDICINAL CHEMISTRY | 2012年 / 19卷 / 16期

关键词：

Peripheral arterial disease; inflammation; hemostatic factors; functional markers; C-REACTIVE PROTEIN; ANKLE-BRACHIAL INDEX; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; FUTURE CARDIOVASCULAR EVENTS; NUTRITION EXAMINATION SURVEY; CRITICAL LIMB ISCHEMIA; CROSS-LINKED FIBRIN; EDINBURGH ARTERY; RISK-FACTORS; D-DIMER;

D O I：

10.2174/092986712800492959

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Patients with peripheral arterial disease (PAD) suffer from increased cardiovascular morbidity and mortality. The ankle brachial index has been widely used as an easy tool to identify and stratify patients with PAD, however its predictive value remains limited. Higher levels of inflammatory and prothrombotic biomarkers have been associated with the development and progression of PAD and recent data suggest that may provide additional information for cardiovascular risk stratification of these patients.

引用

页码：2497 / 2503

页数：7

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