Electrochemical reduction of nitrobenzene via redox-mediated chronoamperometry

被引：11

作者：

Stergiou, Athanasios D. ^{[1
]}

Broadhurst, Daniel H. ^{[1
]}

Symes, Mark D. ^{[1
]}

机构：

[1] Univ Glasgow, WestCHEM, Sch Chem, Univ Ave, Glasgow G12 8QQ, Lanark, Scotland

来源：

STAR PROTOCOLS | 2022年 / 3卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

HYDROGENATION;

D O I：

10.1016/j.xpro.2022.101817

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Anilines are important feedstocks for pharmaceuticals, dyes, and other materials, but traditional approaches to their syntheses usually lack selectivity and environmental sustainability. Here, we describe the selective reduction of nitrobenzene to aniline under mild conditions, using water as the ultimate source of the required protons and electrons. We describe the electrochemical cell assembly, and detail steps for electrochemical reduction followed by organic extraction and analysis of the extracts using NMR. For complete details on the use and execution of this protocol, please refer to Stergiou and Symes (2022a).

引用

页数：14

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