Log-mean Linear Parameterization for Discrete Graphical Models of Marginal Independence and the Analysis of Dichotomizations

被引:2
作者
Roverato, Alberto [1 ]
机构
[1] Univ Bologna, Dept Stat Sci, Bologna, Italy
关键词
contingency table; graphical Markov model; marginal independence; parsimonious model; single-nucleotide polymorphism; GAUSSIAN MODELS; DUALIZATION; ASSOCIATION;
D O I
10.1111/sjos.12126
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We extend the log-mean linear parameterization for binary data to discrete variables with arbitrary number of levels and show that also in this case it can be used to parameterize bi-directed graph models. Furthermore, we show that the log-mean linear parameterization allows one to simultaneously represent marginal independencies among variables and marginal independencies that only appear when certain levels are collapsed into a single one. We illustrate the application of this property by means of an example based on genetic association studies involving single-nucleotide polymorphisms. More generally, this feature provides a natural way to reduce the parameter count, while preserving the independence structure, by means of substantive constraints that give additional insight into the association structure of thevariables.
引用
收藏
页码:627 / 648
页数:22
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