Highly selective and sensitive ratiometric near-infrared fluorescent probe for real-time detection of Hg2+ and its bioapplications in live cells

被引：58
作者：
Jiao, Xiaojie [1 ,2 ]
Liu, Chang [1 ,2 ]
He, Song [1 ,2 ]
Zhao, Liancheng [1 ,3 ]
Zeng, Xianshun [1 ,2 ]
机构：
[1] Tianjin Univ Technol, Sch Mat Sci & Engn, Tianjin Key Lab Photoelect Mat & Devices, Tianjin 300384, Peoples R China
[2] Tianjin Univ Technol, Sch Mat Sci & Engn, Minist Educ, Key Lab Display Mat & Photoelect Devices, Tianjin 300384, Peoples R China
[3] Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Heilongjiang, Peoples R China
来源：
DYES AND PIGMENTS | 2019年 / 160卷
关键词：
Mercury; Chromenylium-cyanine; Fluorescence probe; Near-infrared; Imaging; LIVING CELLS; TURN-ON; ELECTRON-TRANSFER; AQUEOUS-MEDIA; DYE; SENSOR; RHODAMINE; IONS; CHEMOSENSOR; MERCURY;
D O I：
10.1016/j.dyepig.2018.07.040
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A ratiometric near-infrared (NIR) fluorescent probe L based on chromenylium-cyanine fluorophore with chelate unit NS2O2 for the detection of Hg2+ ions in aqueous media has been prepared. The probe L shows high selectivity for Hg2+ ions with immediately fluorescence intensity increasing at 663 nm and decreasing at 728 nm synchronously via a Hg2+-induced intramolecular charge transfer (ICT) mechanism, leading to both "naked-eye" and ratiometric detection of Hg2+ ions in real time. At the same time, the probe exhibits a high sensitivity to Hg2+ in a concentration of ppb range with detection limit of 9.59 nM. Moreover, the probe is cell permeable and low toxic, and can be used in living cells for ratiometric visual monitoring of Hg2+ ions by confocal laser scanning fluorescence microscopy.
引用
收藏
页码：86 / 92
页数：7
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