Fabrication of Scaffolds for Bone-Tissue Regeneration

被引：441

作者：

Chocholata, Petra ^{[1
]}

Kulda, Vlastimil ^{[1
]}

Babuska, Vaclav ^{[1
]}

机构：

[1] Charles Univ Prague, Fac Med Pilsen, Dept Med Chem & Biochem, Karlovarska 48, Plzen 30166, Czech Republic

来源：

MATERIALS | 2019年 / 12卷 / 04期

关键词：

bone tissue engineering; scaffolds; regenerative medicine; stem cells; hydrogels; STEM-CELLS; COMPOSITE SCAFFOLDS; POLYMER SCAFFOLDS; DRUG-DELIVERY; CERAMIC SCAFFOLDS; GELATIN SCAFFOLDS; BIOMATERIALS; CHITOSAN; HYDROGELS; DIFFERENTIATION;

D O I：

10.3390/ma12040568

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The present article describes the state of the art in the rapidly developing field of bone tissue engineering, where many disciplines, such as material science, mechanical engineering, clinical medicine and genetics, are interconnected. The main objective is to restore and improve the function of bone tissue by scaffolds, providing a suitable environment for tissue regeneration and repair. Strategies and materials used in oral regenerative therapies correspond to techniques generally used in bone tissue engineering. Researchers are focusing on developing and improving new materials to imitate the native biological neighborhood as authentically as possible. The most promising is a combination of cells and matrices (scaffolds) that can be fabricated from different kinds of materials. This review summarizes currently available materials and manufacturing technologies of scaffolds for bone-tissue regeneration.

引用

页数：25

共 134 条

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