Cooccurring JAK2 V617F and R1063H mutations increase JAK2 signaling and neutrophilia in myeloproliferative neoplasms

被引:6
|
作者
Mambet, Cristina [1 ,2 ,3 ]
Babosova, Olga [4 ]
Defour, Jean-Philippe [2 ,5 ]
Leroy, Emilie [1 ,2 ]
Necula, Laura [3 ]
Stanca, Oana [6 ,7 ]
Tatic, Aurelia [7 ,8 ]
Berbec, Nicoleta [6 ,7 ]
Coriu, Daniel [7 ,8 ]
Belickova, Monika [9 ]
Kralova, Barbora [10 ]
Lanikova, Lucie [4 ]
Vesela, Jitka [9 ]
Pecquet, Christian [1 ,2 ]
Saussoy, Pascale [5 ]
Havelange, Violaine [11 ]
Diaconu, Carmen C. [3 ]
Divoky, Vladimir [10 ]
Constantinescu, Stefan N. [1 ,2 ,3 ]
机构
[1] Ludwig Inst Canc Res, Brussels Branch, Brussels, Belgium
[2] Catholic Univ Louvain, de Duve Inst, Brussels, Belgium
[3] Stefan S Nicolau Inst Virol, Mol Profiling Myeloproliferat Neoplasms & Acute L, Bucharest, Romania
[4] Acad Sci Czech Republ, Inst Mol Genet, Dept Cell & Dev Biol, Prague, Czech Republic
[5] Catholic Univ Louvain, Clin Univ St Luc, Dept Biol Clin, Brussels, Belgium
[6] Coltea Clin Hosp, Dept Hematol, Bucharest, Romania
[7] Carol Davila Univ Med & Pharm, Dept Radiol Oncol & Hematol, Bucharest, Romania
[8] Fundeni Clin Inst, Ctr Hematol & Bone Marrow Transplantat, Bucharest, Romania
[9] Inst Hematol & Blood Transfus, Prague, Czech Republic
[10] Palacky Univ, Fac Med & Dent, Dept Biol, Hnevotinska 3, CZ-77515 Olomouc, Czech Republic
[11] Clin Univ St Luc, Serv Hematol, Brussels, Belgium
关键词
ESSENTIAL THROMBOCYTHEMIA; POLYCYTHEMIA-VERA;
D O I
10.1182/blood-2018-04-843060
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2695 / 2699
页数:7
相关论文
共 50 条
  • [1] Quantitative assessment of JAK2 V617F and CALR mutations in Philadelphia negative myeloproliferative neoplasms
    Gango, Ambrus
    Mozes, Reka
    Boha, Zsofia
    Kajtar, Bela
    Timar, Botond
    Kiraly, Peter Attila
    Kiss, Richard
    Fesus, Viktoria
    Nagy, Noemi
    Demeter, Judit
    Korosmezey, Gabor
    Borbenyi, Zita
    Marton, Imelda
    Szoke, Anita
    Masszi, Tamas
    Farkas, Peter
    Varkonyi, Judit
    Plander, Mark
    Posfai, Eva
    Egyed, Miklos
    Pal, Katalin
    Radvanyi, Gaspar
    Hamed, Aryan
    Csomor, Judit
    Matolcsy, Andras
    Alpar, Donat
    Bodor, Csaba
    LEUKEMIA RESEARCH, 2018, 65 : 42 - 48
  • [2] Coexistence of lymphoproliferative and myeloproliferative neoplasms with simultaneous CALR and JAK2 V617F mutations
    Yang, Hai-Su
    CANCER BIOMARKERS, 2016, 17 (04) : 383 - 389
  • [3] CALR mutations in a cohort of JAK2 V617F negative patients with suspected myeloproliferative neoplasms
    Mikic, Tanja Belcic
    Pajic, Tadej
    Sever, Matjaz
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [4] JAK2 V617F Mutation Prevalence in Myeloproliferative Neoplasms in Pernambuco, Brazil
    da Silva, Rafael Ramos
    Domingues Hatzlhofer, Betania Lucena
    de Faria Machado, Cintia Gonsalves
    de Melo Lima, Aleide Santos
    de Albuquerque, Dulcineia Martins
    Nunes dos Santos, Magnun Nueldo
    Fertrin, Kleber Yotsumoto
    Costa, Fernando Ferreira
    Araujo, Aderson da Silva
    Cavalcanti Bezerra, Marcos Andre
    GENETIC TESTING AND MOLECULAR BIOMARKERS, 2012, 16 (07) : 802 - 805
  • [5] Analysis of JAK2 V617F mutation in Tunisian patients with myeloproliferative neoplasms
    Chadi, Soumaya
    Dhaouadi, Tarak
    Sfar, Imen
    Baccouche, Hela
    Nabli, Rym
    Ben Romdhane, Neila
    Ben Abdallah, Taieb
    Gorgi, Yousr
    EUROPEAN JOURNAL OF INFLAMMATION, 2021, 19
  • [6] JAK2 V617F and beyond: role of genetics and aberrant signaling in the pathogenesis of myeloproliferative neoplasms
    Oh, Stephen T.
    Gotlib, Jason
    EXPERT REVIEW OF HEMATOLOGY, 2010, 3 (03) : 323 - 337
  • [7] The V617F JAK2 mutation and the myeloproliferative disorders
    Percy, MJ
    McMullin, MF
    HEMATOLOGICAL ONCOLOGY, 2005, 23 (3-4) : 91 - 93
  • [8] Detection of JAK2 V617F mutation increases the diagnosis of myeloproliferative neoplasms
    Zhang, Shu-Peng
    Li, Hui
    Lai, Ren-Sheng
    ONCOLOGY LETTERS, 2015, 9 (02) : 735 - 738
  • [9] The JAK2 V617F Mutation in Pediatric Myeloproliferative Neoplasms: How and When?
    Langabeer, Stephen E.
    Smith, Owen P.
    McMahon, Corrina
    PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2014, 31 (02) : 138 - 139
  • [10] New advances in the role of JAK2 V617F mutation in myeloproliferative neoplasms
    Zhang, Yongchao
    Zhao, Yue
    Liu, YuSi
    Zhang, Minyu
    Zhang, Jihong
    CANCER, 2024, 130 (24) : 4229 - 4240