Nonparametric estimation for length-biased and right-censored data

被引:64
作者
Huang, Chiung-Yu [1 ]
Qin, Jing [1 ]
机构
[1] NIAID, Biostat Res Branch, NIH, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
Backward and forward recurrence time; Cross-sectional sampling; Partial likelihood; Random truncation; Renewal process; PRODUCT-LIMIT ESTIMATOR; PREVALENT COHORT DATA; SURVIVAL-DATA; TRUNCATION;
D O I
10.1093/biomet/asq069
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
This paper considers survival data arising from length-biased sampling, where the survival times are left truncated by uniformly distributed random truncation times. We propose a nonparametric estimator that incorporates the information about the length-biased sampling scheme. The new estimator retains the simplicity of the truncation product-limit estimator with a closed-form expression, and has a small efficiency loss compared with the nonparametric maximum likelihood estimator, which requires an iterative algorithm. Moreover, the asymptotic variance of the proposed estimator has a closed form, and a variance estimator is easily obtained by plug-in methods. Numerical simulation studies with practical sample sizes are conducted to compare the performance of the proposed method with its competitors. A data analysis of the Canadian Study of Health and Aging is conducted to illustrate the methods and theory.
引用
收藏
页码:177 / 186
页数:10
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