The longitudinal relationships between pain severity and disability versus health-related quality of life and costs among chronic low back pain patients

被引:76
作者
Mutubuki, E. N. [1 ]
Beljon, Y. [1 ]
Maas, E. T. [1 ,2 ]
Huygen, F. J. P. M. [3 ]
Ostelo, R. W. J. G. [1 ,4 ]
van Tulder, M. W. [1 ,5 ]
van Dongen, J. M. [1 ]
机构
[1] Vrije Univ Amsterdam, Amsterdam Movement Sci, Fac Sci, Dept Hlth Sci, Amsterdam, Netherlands
[2] Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada
[3] ErasmusMC, Dept Anesthesiol, Ctr Pain Med, Rotterdam, Netherlands
[4] Vrije Univ Amsterdam Med Ctr, Amsterdam Movement Sci, Dept Epidemiol & Biostat, Amsterdam, Netherlands
[5] Aarhus Univ Hosp, Dept Physiotherapy & Occupat Therapy, Aarhus, Denmark
关键词
Pain; Disability; Health-related quality of life; Societal costs; Longitudinal analysis; Low back pain; PSYCHOMETRIC PROPERTIES; CLINICAL-TRIALS; INTENSITY; QUESTIONNAIRE; OUTCOMES; EQ-5D; CARE; RESPONSIVENESS; INSTRUMENT; SCALE;
D O I
10.1007/s11136-019-02302-w
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Purpose Previous studies found higher levels of pain severity and disability to be associated with higher costs and lower health-related quality of life. However, these findings were based on cross-sectional data and little is known about the longitudinal relationships between pain severity and disability versus health-related quality of life and costs among chronic low back pain patients. This study aims to cover this knowledge gap by exploring these longitudinal relationships in a consecutive cohort. Methods Data of 6316 chronic low back pain patients were used. Measurements took place at 3, 6, 9, and 12 months. Pain severity (Numeric pain rating scale; range: 0-100), disability (Oswestry disability index; range: 0-100), health-related quality of life (EQ-5D-3L: range: 0-1), societal and healthcare costs (cost questionnaire) were measured. Using linear generalized estimating equation analyses, longitudinal relationships were explored between: (1) pain severity and health-related quality of life, (2) disability and health-related quality of life, (3) pain severity and societal costs, (4) disability and societal costs, (5) pain severity and healthcare costs, and (6) disability and healthcare costs. Results Higher pain and disability levels were statistically significantly related with poorer health-related quality of life (pain intensity: - 0.0041; 95% CI - 0.0043 to - 0.0039; disability: - 0.0096; 95% CI - 0.0099 to - 0.0093), higher societal costs (pain intensity: 7; 95% CI 5 to 8; disability: 23; 95% CI 20 to 27) and higher healthcare costs (pain intensity: 3; 95% CI 2 to 4; disability: 9; 95% CI 7 to 11). Conclusion Pain and disability were longitudinally related to health-related quality of life, societal costs, and healthcare costs. Disability had a stronger association with all outcomes compared to pain.
引用
收藏
页码:275 / 287
页数:13
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