THE PHENYLALANYL-TRNA SYNTHETASE IS A DRUGGABLE TARGET IN PLASMODIUM FALCIPARUM

被引:0
作者
Sakata-Kato, Tomoyo [1 ]
Kato, Nobutaka [2 ]
Comer, Eamon [2 ]
Lukens, Amanda K. [2 ]
Corey, Victoria C. [3 ]
Winzeler, Elizabeth A. [3 ]
Scherer, Christina A. [2 ]
Schreiber, Stuart L. [2 ]
Wirth, Dyann F. [1 ]
机构
[1] Harvard TH Chan Sch Publ Hlth, Boston, MA USA
[2] Broad Inst, Cambridge, MA USA
[3] Univ Calif San Diego, Sch Med, La Jolla, CA 92093 USA
关键词
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
1206
引用
收藏
页码:367 / 367
页数:1
相关论文
共 50 条
[31]   Phenylalanyl-tRNA synthetase interacts with DNA: Studies on activity rising deoxyribooligonucleotides [J].
Ivanov, KA ;
Moor, NA ;
Ankilova, VN ;
Lavrik, OI .
BIOCHEMISTRY-MOSCOW, 2000, 65 (04) :436-441
[32]   Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase [J].
Sonoiki, Ebere ;
Palencia, Andres ;
Guo, Denghui ;
Ahyong, Vida ;
Dong, Chen ;
Li, Xianfeng ;
Hernandez, Vincent S. ;
Zhang, Yong-Kang ;
Choi, Wai ;
Gut, Jiri ;
Legac, Jennifer ;
Cooper, Roland ;
Alley, M. R. K. ;
Freund, Yvonne R. ;
DeRisi, Joseph ;
Cusack, Stephen ;
Rosenthal, Philip J. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2016, 60 (08) :4886-4895
[33]   The crystal structure of phenylalanyl-tRNA synthetase from Thermus thermophilus complexed with cognate tRNA(Phe) [J].
Goldgur, Y ;
Mosyak, L ;
Reshetnikova, L ;
Ankilova, V ;
Lavrik, O ;
Khodyreva, S ;
Safro, M .
STRUCTURE, 1997, 5 (01) :59-68
[34]   Crystallization and X-ray analysis of human cytoplasmic phenylalanyl-tRNA synthetase [J].
Finarov, Igal ;
Moor, Nina ;
Kessler, Naama ;
Safro, Mark .
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2009, 65 :93-97
[35]   Oxidation alters the architecture of the phenylalanyl-tRNA synthetase editing domain to confer hyperaccuracy [J].
Srinivas, Pooja ;
Steiner, Rebecca E. ;
Pavelich, Ian J. ;
Guerrero-Ferreira, Ricardo ;
Juneja, Puneet ;
Ibba, Michael ;
Dunham, Christine M. .
NUCLEIC ACIDS RESEARCH, 2021, 49 (20) :11800-11809
[36]   Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase [J].
Montgomery, Justin I. ;
Toogood, Peter L. ;
Hutchings, Kim M. ;
Liu, Jia ;
Narasimhan, Lakshmi ;
Braden, Timothy ;
Dermyer, Michael R. ;
Kulynych, Angela D. ;
Smith, Yvonne D. ;
Warmus, Joseph S. ;
Taylor, Clarke .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (03) :665-669
[37]   Mitochondrial phenylalanyl-tRNA synthetase mutations underlie fatal infantile Alpers encephalopathy [J].
Elo, Jenni M. ;
Yadavalli, Srujana S. ;
Euro, Liliya ;
Isohanni, Pirjo ;
Gotz, Alexandra ;
Carroll, Christopher J. ;
Valanne, Leena ;
Alkuraya, Fowzan S. ;
Uusimaa, Johanna ;
Paetau, Anders ;
Caruso, Eric M. ;
Pihko, Helena ;
Ibba, Michael ;
Tyynismaa, Henna ;
Suomalainen, Anu .
HUMAN MOLECULAR GENETICS, 2012, 21 (20) :4521-4529
[38]   Cloning and characterization of the phenylalanyl-tRNA synthetase β subunit gene from Candida albicans [J].
Marcilla, A ;
Pallotti, C ;
Gomez-Lobo, M ;
Caballero, P ;
Valentin, E ;
Sentandreu, R .
FEMS MICROBIOLOGY LETTERS, 1998, 161 (01) :179-185
[39]   Phenylalanyl-tRNA synthetase from the archaeon Methanobacterium thermoautotrophicum is an (αβ)2 heterotetrameric protein [J].
Das, R ;
Vothknecht, UC .
BIOCHIMIE, 1999, 81 (11) :1037-1039
[40]   Reversible inactivation of yeast mitochondrial phenylalanyl-tRNA synthetase under oxidative stress [J].
Chakraborty, Shruti ;
Ganguli, Sayak ;
Chowdhury, Aritra ;
Ibba, Michael ;
Banerjee, Rajat .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2018, 1862 (08) :1801-1809