Malnutrition in Older Adults-Recent Advances and Remaining Challenges

被引:344
作者
Norman, Kristina [1 ,2 ,3 ,4 ,5 ,6 ]
Hass, Ulrike [4 ,5 ]
Pirlich, Matthias [7 ]
机构
[1] Charite Univ Med Berlin, Dept Geriatr & Med Gerontol, D-13347 Berlin, Germany
[2] Free Univ Berlin, D-13347 Berlin, Germany
[3] Humboldt Univ, D-13347 Berlin, Germany
[4] German Inst Human Nutr Potsdam Rehbrucke, Dept Nutr & Gerontol, D-14458 Nuthetal, Germany
[5] Univ Potsdam, Inst Nutr Sci, D-14458 Nuthetal, Germany
[6] German Ctr Cardiovasc Res DZHK, Partner Site Berlin, D-10115 Berlin, Germany
[7] Imperial Oak Outpatient Clin Endocrinol & Gastroe, D-12159 Berlin, Germany
关键词
malnutrition; ageing; inflammaging; sarcopenia; anorexia of aging; micronutrients; DoMAP; GLIM criteria; PROTEIN-ENERGY MALNUTRITION; CENTRAL-NERVOUS-SYSTEM; BONE-MINERAL DENSITY; GERIATRIC SYNDROMES; BODY-COMPOSITION; IMMUNE FUNCTION; MUSCLE MASS; RISK-FACTOR; COMMUNITY; AGE;
D O I
10.3390/nu13082764
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Malnutrition in older adults has been recognised as a challenging health concern associated with not only increased mortality and morbidity, but also with physical decline, which has wide ranging acute implications for activities of daily living and quality of life in general. Malnutrition is common and may also contribute to the development of the geriatric syndromes in older adults. Malnutrition in the old is reflected by either involuntary weight loss or low body mass index, but hidden deficiencies such as micronutrient deficiencies are more difficult to assess and therefore frequently overlooked in the community-dwelling old. In developed countries, the most cited cause of malnutrition is disease, as both acute and chronic disorders have the potential to result in or aggravate malnutrition. Therefore, as higher age is one risk factor for developing disease, older adults have the highest risk of being at nutritional risk or becoming malnourished. However, the aetiology of malnutrition is complex and multifactorial, and the development of malnutrition in the old is most likely also facilitated by ageing processes. This comprehensive narrative review summarizes current evidence on the prevalence and determinants of malnutrition in old adults spanning from age-related changes to disease-associated risk factors, and outlines remaining challenges in the understanding, identification as well as treatment of malnutrition, which in some cases may include targeted supplementation of macro- and/or micronutrients, when diet alone is not sufficient to meet age-specific requirements.
引用
收藏
页数:20
相关论文
共 165 条
  • [21] Cederholm T, 2019, J CACHEXIA SARCOPENI, V10, P207, DOI [10.1016/j.clnu.2018.08.002, 10.1002/jcsm.12383, 10.1002/jpen.1440, 10.1016/j.clnu.2019.02.033]
  • [22] Nutritional status in older persons according to healthcare setting: A systematic review and meta-analysis of prevalence data using MNA®
    Cereda, Emanuele
    Pedrolli, Carlo
    Klersy, Catherine
    Bonardi, Chiara
    Quarleri, Lara
    Cappello, Silvia
    Turri, Annalisa
    Rondanelli, Mariangela
    Caccialanza, Riccardo
    [J]. CLINICAL NUTRITION, 2016, 35 (06) : 1282 - 1290
  • [23] Mini Nutritional Assessment
    Cereda, Emanuele
    [J]. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2012, 15 (01) : 29 - 41
  • [24] Cesari M, 2004, AM J CLIN NUTR, V79, P289
  • [25] Bone mineral density and body composition in underweight and normal elderly subjects
    Coin, A
    Sergi, G
    Benincà, P
    Lupoli, L
    Cinti, G
    Ferrara, L
    Benedetti, G
    Tomasi, G
    Pisent, C
    Enzi, G
    [J]. OSTEOPOROSIS INTERNATIONAL, 2000, 11 (12) : 1043 - 1050
  • [26] Mitochondria, immunosenescence and inflammaging: a role for mitokines?
    Conte, Maria
    Martucci, Morena
    Chiariello, Antonio
    Franceschi, Claudio
    Salvioli, Stefano
    [J]. SEMINARS IN IMMUNOPATHOLOGY, 2020, 42 (05) : 607 - 617
  • [27] Human Aging and Longevity Are Characterized by High Levels of Mitokines
    Conte, Maria
    Ostan, Rita
    Fabbri, Cristina
    Santoro, Aurelia
    Guidarelli, Giulia
    Vitale, Giovanni
    Mari, Daniela
    Sevini, Federica
    Capri, Miriam
    Sandri, Marco
    Monti, Daniela
    Franceschi, Claudio
    Salvioli, Stefano
    [J]. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2019, 74 (05): : 600 - 607
  • [28] Prevalence and Predictors of Subclinical Micronutrient Deficiency in German Older Adults: Results from the Population-Based KORA-Age Study
    Conzade, Romy
    Koenig, Wolfgang
    Heier, Margit
    Schneider, Andrea
    Grill, Eva
    Peters, Annette
    Thorand, Barbara
    [J]. NUTRIENTS, 2017, 9 (12)
  • [29] Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL knowledge hub project
    Correa-Perez, Andrea
    Abraha, Iosef
    Cherubini, Antonio
    Collinson, Avril
    Dardevet, Dominique
    de Groot, Lisette C. P. G. M.
    de van der Schueren, Marian A. E.
    Hebestreit, Antje
    Hickson, Mary
    Jaramillo-Hidalgo, Javier
    Lozano-Montoya, Isabel
    O'Mahony, Denis
    Soiza, Roy L.
    Visser, Marjolein
    Volkert, Dorothee
    Wolters, Maike
    Cruz Jentoft, Alfonso J.
    [J]. AGEING RESEARCH REVIEWS, 2019, 49 : 27 - 48
  • [30] Assessment and Treatment of the Anorexia of Aging: A Systematic Review
    Cox, Natalie J.
    Ibrahim, Kinda
    Sayer, Avan A.
    Robinson, Sian M.
    Roberts, Helen C.
    [J]. NUTRIENTS, 2019, 11 (01):