4-[(1-Hydroxy-2-naphthyl)methyleneamino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one

被引：7

作者：

Liang, Qiang ^{[1
]}

Wang, Qian ^{[1
]}

机构：

[1] Qingdao Univ, Teachers Coll, Dept Chem, Qingdao 266071, Shandong, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷

关键词：

RAY CRYSTAL-STRUCTURE; ANTI-CANCER DRUGS; SCHIFF-BASE; S-BENZYLDITHIOCARBAZATE; ANTIMICROBIAL ACTIVITY; LIQUID-CHROMATOGRAPHY; ANTIPYRINE; COMPLEXES; PALLADIUM(II); DERIVATIVES;

D O I：

10.1107/S1600536810026450

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title antipyrine derivative, C22H19N3O2, was synthesized by the reaction of 4-amino-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one and 1-hydroxynaphthalene-2-carbaldehyde in methanol solution. As expected, the compound adopts a trans configuration about the central C=N bond. The N atom is involved in an intramolecular O-H...N bond which stabilizes the molecular configuration. In the crystal structure, adjacent molecules stack with no short contacts.

引用

页码：O1968 / U766

页数：12

共 34 条

[1] The inhibition of 4-(2′-amino-5′-methylphenylazo) antipyrine on corrosion of mild steel in HCl solution [J].

Abd El Rehim, SS ;

Ibrahim, MAM ;

Khalid, KF .

MATERIALS CHEMISTRY AND PHYSICS, 2001, 70 (03) :268-273

[2] Biological activity of palladium(II) and platinum(II) complexes of the acetone Schiff bases of S-methyl- and S-benzyldithiocarbazate and the X-ray crystal structure of the [Pd(asme)2] (asme=anionic form of the acetone Schiff base of S-methyldithiocarbazate) complex [J].

Ali, MA ;

Mirza, AH ;

Butcher, RJ ;

Tarafder, MTH ;

Keat, TB ;

Ali, AM .

JOURNAL OF INORGANIC BIOCHEMISTRY, 2002, 92 (3-4) :141-148

[3]

[Anonymous], 1992, Pharm. Chem. J., DOI DOI 10.1007/BF00772907

[4] Concurrent determination of topotecan and model permeability markers (atenolol, antipyrine, propranolol and furosemide) by reversed phase liquid chromatography: Utility in Caco-2 intestinal absorption studies [J].

Bansal, Tripta ;

Singh, Manoj ;

Mishra, Gautam ;

Talegaonkar, Sushama ;

Khar, Roop K. ;

Jaggi, Manu ;

Mukherjee, Rama .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 859 (02) :261-266

[5] Electrochemical, quantum-chemical and antioxidant properties of antipyrine and its derivatives [J].

Bashkatova, NV ;

Korotkova, EI ;

Karbainov, YA ;

Yagovkin, AY ;

Bakibaev, AA .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2005, 37 (05) :1143-1147

[6] Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety [J].

Bondock, Samir ;

Rabie, Ramy ;

Etman, Hassan A. ;

Fadda, Ahmed A. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (10) :2122-2129

[7]

Bruker, 2002, SMART SAINT PLUS

[8]

CAPEL ID, 1978, BIOCHEM PHARMACOL, V27, P1413, DOI 10.1016/0006-2952(78)90093-X

[9] Simultaneous spectrophotometric-multivariate calibration determination of several components of ophthalmic solutions: phenylephrine, chloramphenicol, antipyrine, methylparaben and thimerosal [J].

Collado, MS ;

Mantovani, VE ;

Goicoechea, HC ;

Olivieri, AC .

TALANTA, 2000, 52 (05) :909-920

[10] Determination of phenolic derivatives of antipyrine in plasma with solid-phase extraction and high-performance liquid chromatography-atmospheric-pressure chemical ionization mass spectrometry [J].

Coolen, SAJ ;

Ligor, T ;

van Lieshout, M ;

Huf, FA .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1999, 732 (01) :103-113

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