Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells

被引:16
作者
Johnson, Rachel M. Gibbons [1 ]
Wen, Ti [2 ,3 ]
Dong, Haidong [2 ,3 ]
机构
[1] Univ Minnesota, Biol Discipline, Morris, MN 56267 USA
[2] Mayo Clin, Coll Med & Sci, Dept Urol, Rochester, MN 55905 USA
[3] Mayo Clin, Coll Med & Sci, Dept Immunol, Rochester, MN 55905 USA
关键词
B7-H1;
D O I
10.1038/s41590-020-0599-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
PD-L1 expressed by T cells provides backward and forward signals to restrain both innate and adaptive immune responses in tumor tissues.
引用
收藏
页码:365 / 366
页数:2
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