Rhodium(II)-Catalyzed Cross-Coupling of Diazo Compounds

被引：105

作者：

Hansen, Jorn H. ^{[1
]}

Parr, Brendan T. ^{[1
]}

Pelphrey, Philip ^{[2
]}

Jin, Quihui ^{[2
]}

Autschbach, Jochen ^{[2
]}

Davies, Huw M. L. ^{[1
]}

机构：

[1] Emory Univ, Dept Chem, Atlanta, GA 30322 USA

[2] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 11期

基金：

美国国家科学基金会;

关键词：

alkenes; carbenoids; cross-coupling reactions; diazo compounds; C-H ACTIVATION; STEREOSELECTIVE DECOMPOSITION; CATALYZED DECOMPOSITION; OLEFIN-METATHESIS; CARBENE CATALYST; CIS-ALKENES; COMPLEXES; TRANSFORMATIONS; DIAZOACETATES; SELECTIVITY;

D O I：

10.1002/anie.201004923

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identified by ReactIR and DFT calculations and provide a framework for the design of viable diazo coupling reactions. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2544 / 2548

页数：5

共 53 条

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