Dietary protein level and probiotic supplementation effects on piglet response to Escherichia coli K88 challenge: Performance and gut microbial population

被引:35
作者
Bhandari, S. K. [1 ]
Opapeju, F. O. [1 ]
Krause, D. O. [1 ]
Nyachoti, C. M. [1 ]
机构
[1] Univ Manitoba, Dept Anim Sci, Winnipeg, MB R3T 2N2, Canada
关键词
Pigs; Escherichia coli K88; Crude motein; Probiotic; WEANED PIGS; GROWTH-PERFORMANCE; HEALTH; INDICATORS; INFECTION;
D O I
10.1016/j.livsci.2010.06.060
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Thirty-six piglets weaned on day 21 were used to investigate the effect of dietary crude protein (CP) and non-pathogenic Escherichia coli probiotic on performance of piglets subjected to E. coli 1(88 challenge in a 12-d study. A 2 x 3 factorial arrangement with two levels of CP (HP, 22% vs LP 17%) and three additives types (no additive, NA; in-feed antibiotic. AB: and probiotic, PRO) constituted the 6 treatments. The PRO diets were prepared each morning by mixing 50 ml of 9 x 10(10) cfu/ml of fresh probiotic cultures with fresh feed. After a 6-d adaptation period, pigs were orally inoculated with a 6 ml of E. coli K88 (2 x 10(10) cfu/ml). Pigs fed the LP diets had higher ADG during pre- and post-inoculation period than pigs fed the HP diets. The LP fed pigs plus PRO had superior (P<0.05) ADG post-inoculation compared to the AB treatment. Pigs fed with LP diets had lower (P<0.05) post-inoculation FC scores than pigs fed with HP diets. Heal mucosal counts of E. coli K88 were lower (P<0.05) for the AB and PRO treatments 7 d post-challenge than other treatments. In conclusion, the 17% dietary CP level resulted in superior performance in piglets than 22% dietary CP level and the LP diet and E. coli-based probiotic acted synergistically resulting in better performance in post-weaning piglets. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:185 / 188
页数:4
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