A Quality Improvement Initiative to Reduce Hospitalizations for Low-risk Diabetic Ketoacidosis

被引:7
作者
Bergmann, Kelly R. [1 ]
Abuzzahab, M. Jennifer [4 ]
Arms, Joe [1 ]
Cutler, Gretchen [1 ]
Vander Velden, Heidi [1 ]
Simper, Ted [2 ]
Christensen, Eric [5 ]
Watson, Dave [3 ]
Kharbanda, Anupam [1 ]
机构
[1] Childrens Minnesota, Dept Emergency Med, 2525 Chicago Ave South,Mail Stop 32-1488, St Paul, MN 55404 USA
[2] Childrens Minnesota, Dept Pharm, St Paul, MN USA
[3] Childrens Minnesota, Res & Sponsored Programs, St Paul, MN USA
[4] Childrens Minnesota, Pediat Endocrinol & McNeely Diabet Ctr, St Paul, MN USA
[5] Univ Minnesota, Coll Continuing & Profess Studies, Minneapolis, MN USA
关键词
SUBCUTANEOUS INSULIN LISPRO; RANDOMIZED CONTROLLED-TRIAL; CEREBRAL EDEMA; OUTPATIENT MANAGEMENT; REGULAR INSULIN; YOUNG-PEOPLE; CHILDREN; TYPE-1; ADOLESCENTS; PREVALENCE;
D O I
10.1542/peds.2019-1104
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
BACKGROUND AND OBJECTIVES: Children with established type 1 diabetes (T1D) who present to the emergency department (ED) with mild diabetic ketoacidosis (DKA) are often hospitalized, although outpatient management may be appropriate. Our aim was to reduce hospitalization rates for children with established T1D presenting to our ED with mild DKA who were considered low risk for progression of illness. METHODS: We conducted a quality improvement initiative between January 1, 2012, and December 31, 2018 among children and young adults <= 21 years of age with established T1D presenting to our tertiary care ED with low-risk DKA. Children transferred to our institution were excluded. DKA severity was classified as low, medium, or high risk on the basis of laboratory and clinical criteria. Our quality improvement initiative consisted of development and implementation of an evidence-based treatment guideline after review by a multidisciplinary team. Our primary outcome was hospitalization rate, and our balancing measure was 3-day ED revisits. Statistical process control methods were used to evaluate outcome changes. RESULTS: We identified 165 patients presenting with low-risk DKA. The baseline preimplementation hospitalization rate was 74% (95% confidence interval 64%-82%), and after implementation, this decreased to 55% (95% confidence interval 42%-67%) (219%; P=.011). The postimplementation hospitalization rate revealed special cause variation. One patient in the postimplementation period returned to the ED within 3 days but did not have DKA and was not hospitalized. CONCLUSIONS: Hospitalization rates for children and young adults presenting to the ED with low-risk DKA can be safely reduced without an increase in ED revisits.
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页数:8
相关论文
共 34 条
[1]   Children and Adolescents: Standards of Medical Care in Diabetes-2018 [J].
不详 .
DIABETES CARE, 2018, 41 :S126-S136
[2]   EFFECT OF VOLUME OF FLUID RESUSCITATION ON METABOLIC NORMALIZATION IN CHILDREN PRESENTING IN DIABETIC KETOACIDOSIS: A RANDOMIZED CONTROLLED TRIAL [J].
Bakes, Katherine ;
Haukoos, Jason S. ;
Deakyne, Sara J. ;
Hopkins, Emily ;
Easter, Josh ;
McFann, Kim ;
Brent, Alison ;
Rewers, Arleta .
JOURNAL OF EMERGENCY MEDICINE, 2016, 50 (04) :551-559
[3]   Statistical process control as a tool for research and healthcare improvement [J].
Benneyan, JC ;
Lloyd, RC ;
Plsek, PE .
QUALITY & SAFETY IN HEALTH CARE, 2003, 12 (06) :458-464
[4]   OUTPATIENT MANAGEMENT OF DIABETIC-KETOACIDOSIS [J].
BONADIO, WA ;
GUTZEIT, MF ;
LOSEK, JD ;
SMITH, DS .
AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1988, 142 (04) :448-450
[5]   PEDIATRIC DIABETIC-KETOACIDOSIS - PATHOPHYSIOLOGY AND POTENTIAL FOR OUTPATIENT MANAGEMENT OF SELECTED CHILDREN [J].
BONADIO, WA .
PEDIATRIC EMERGENCY CARE, 1992, 8 (05) :287-290
[6]  
Chiari Giovanni, 2003, Acta Biomed, V74 Suppl 1, P45
[7]   Subcutaneous regular insulin for the treatment of diabetic ketoacidosis in children [J].
Cohen, Michal ;
Leibovitz, Noa ;
Shilo, Smadar ;
Zuckerman-Levin, Nehama ;
Shavit, Itai ;
Shehadeh, Naim .
PEDIATRIC DIABETES, 2017, 18 (04) :290-296
[8]   Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009 [J].
Dabelea, Dana ;
Mayer-Davis, Elizabeth J. ;
Saydah, Sharon ;
Imperatore, Giuseppina ;
Linder, Barbara ;
Divers, Jasmin ;
Bell, Ronny ;
Badaru, Angela ;
Talton, Jennifer W. ;
Crume, Tessa ;
Liese, Angela D. ;
Merchant, Anwar T. ;
Lawrence, Jean M. ;
Reynolds, Kristi ;
Dolan, Lawrence ;
Liu, Lenna L. ;
Hamman, Richard F. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 311 (17) :1778-1786
[9]   Trends in the Prevalence of Ketoacidosis at Diabetes Diagnosis: The SEARCH for Diabetes in Youth Study [J].
Dabelea, Dana ;
Rewers, Arleta ;
Stafford, Jeanette M. ;
Standiford, Debra A. ;
Lawrence, Jean M. ;
Saydah, Sharon ;
Imperatore, Giuseppina ;
D'Agostino, Ralph B., Jr. ;
Mayer-Davis, Elizabeth J. ;
Pihoker, Catherine .
PEDIATRICS, 2014, 133 (04) :E938-E945
[10]   Subcutaneous use of a fast-acting insulin analog - An alternative treatment for pediatric patients with diabetic ketoacidosis [J].
Della Manna, T ;
Steinmetz, L ;
Campos, PR ;
Farhat, SCL ;
Schvartsman, C ;
Kuperman, H ;
Setian, N ;
Damiani, D .
DIABETES CARE, 2005, 28 (08) :1856-1861