A Fast CEA Analyzer Prototype for Point of Care Testing

被引：0

作者：

Wang, Chua-Chin ^{[1
]}

Liao, Chiang-Hsiang ^{[1
]}

Chang, Chia-Ming

Lan, Je-Wei

Huang, I-Yu ^{[1
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Elect Engn, Kaohsiung 80424, Taiwan

来源：

2014 IEEE INTERNATIONAL CONFERENCE ON ELECTRON DEVICES AND SOLID-STATE CIRCUITS (EDSSC) | 2014年

关键词：

CEA measurement; frequency-shift readout circuit; FPW; resonant frequency; point of care testing (POCT);

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A CEA (carcinoembryonic antigen) concentration analyzer prototype using a pair of two-port FPW (flexural plate-wave) sensors is proposed in this paper. The proposed prototype utilizes a frequency-shift readout method based upon a peak detecting scheme to measure the resonant frequency shift. The frequency-shift readout circuit is integrated on silicon composed of a linear frequency generator, two peak detectors, two registers, and a subtractor. The frequency scanning range is from 0.9 MHz to 22.4 MHz according to the characteristics of the FPW biosensor. The sensitivity of the peak detector is 5 mV. The proposed frequency-shift readout circuit is verified by a PCB-based prototype, where the CEA serum titration is stabilized after 10 minutes and the linearity of the concentration vs. frequency shift is 97.72%.

引用

页数：2

共 6 条

[1] Phase detection of the two-port FPW sensor for biosensing [J].