Oxytocin and microglia in the development of social behaviour

被引：13

作者：

Gonzalez, Alicia ^{[1
]}

Hammock, Elizabeth A. D. ^{[1
]}

机构：

[1] Florida State Univ, Dept Psychol, Program Neurosci, 1107 West Call St, Tallahassee, FL 32306 USA

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2022年 / 377卷 / 1858期

基金：

美国国家卫生研究院;

关键词：

oxytocin; microglia; development; social behaviour; sex differences; NF-KAPPA-B; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MESSENGER-RIBONUCLEIC-ACID; ESTROGEN-RECEPTOR BETA; NECROSIS-FACTOR-ALPHA; TNF-ALPHA; CRITICAL PERIOD; AMPA-RECEPTOR; NITRIC-OXIDE; SPINAL-CORD;

D O I：

10.1098/rstb.2021.0059

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Oxytocin is a well-established regulator of social behaviour. Microglia, the resident immune cells of the central nervous system, regulate brain development and maintenance in health and disease. Oxytocin and microglia interact: microglia appear to regulate the oxytocin system and are, in turn, regulated by oxytocin, which appears to have anti-inflammatory effects. Both microglia and oxytocin are regulated in sex-specific ways. Oxytocin and microglia may work together to promote experience-dependent circuit refinement through multiple developmental-sensitive periods contributing to individual differences in social behaviour.This article is part of the theme issue 'Interplays between oxytocin and other neuromodulators in shaping complex social behaviours'.

引用

页数：16

共 234 条

[51] Oxytocin, Neural Plasticity, and Social Behavior [J].

Froemke, Robert C. ;

Young, Larry J. .

ANNUAL REVIEW OF NEUROSCIENCE, VOL 44, 2021, 2021, 44 :359-381

[52] Microglia: Architects of the Developing Nervous System [J].

Frost, Jeffrey L. ;

Schafer, Dorothy P. .

TRENDS IN CELL BIOLOGY, 2016, 26 (08) :587-597

[53] Effect of metritis on endometrium tissue transcriptome during puerperium in Holstein lactating cows [J].

Genis, Sandra ;

Aris, Anna ;

Kaur, Manveen ;

Cerri, Ronaldo L. A. .

THERIOGENOLOGY, 2018, 122 :116-123

[54] Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages [J].

Ginhoux, Florent ;

Greter, Melanie ;

Leboeuf, Marylene ;

Nandi, Sayan ;

See, Peter ;

Gokhan, Solen ;

Mehler, Mark F. ;

Conway, Simon J. ;

Ng, Lai Guan ;

Stanley, E. Richard ;

Samokhvalov, Igor M. ;

Merad, Miriam .

SCIENCE, 2010, 330 (6005) :841-845

[55]

Gottschalk Michael G, 2018, Curr Top Behav Neurosci, V35, P467, DOI 10.1007/7854_2017_25

[56] Annotation: Attachment disorganisation and psychopathology: new findings in attachment research and their potential implications for developmental psychopathology in childhood [J].

Green, J ;

Goldwyn, R .

JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 2002, 43 (07) :835-846

[57] Genomic and epigenetic evidence for oxytocin receptor deficiency in autism [J].

Gregory, Simon G. ;

Connelly, Jessica J. ;

Towers, Aaron J. ;

Johnson, Jessica ;

Biscocho, Dhani ;

Markunas, Christina A. ;

Lintas, Carla ;

Abramson, Ruth K. ;

Wright, Harry H. ;

Ellis, Peter ;

Langford, Cordelia F. ;

Worley, Gordon ;

Delong, G. Robert ;

Murphy, Susan K. ;

Cuccaro, Michael L. ;

Persico, Antonello ;

Pericak-Vance, Margaret A. .

BMC MEDICINE, 2009, 7

[58] Oxytocin Revisited: Its Role in Cardiovascular Regulation [J].

Gutkowska, J. ;

Jankowski, M. .

JOURNAL OF NEUROENDOCRINOLOGY, 2012, 24 (04) :599-608

[59] Developmental Perspectives on Oxytocin and Vasopressin [J].

Hammock, Elizabeth A. D. .

NEUROPSYCHOPHARMACOLOGY, 2015, 40 (01) :24-42

[60] Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity [J].

Hanamsagar, Richa ;

Alter, Mark D. ;

Block, Carina S. ;

Sullivan, Haley ;

Bolton, Jessica L. ;

Bilbo, Staci D. .

GLIA, 2017, 65 (09) :1504-1520

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