Alzheimer's failure raises questions about disease-modifying strategies

被引:131
作者
Extance, Andy
机构
关键词
D O I
10.1038/nrd3288
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Do the lack of efficacy and the increase in the risk of skin cancer seen in Phase III trials of Eli Lilly's γ-secretase inhibitor undermine the potential of targeting this enzyme for the treatment of Alzheimer's disease?
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页码:749 / U87
页数:3
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