CT Assessment of Myocardial Perfusion and Fractional Flow Reserve in Coronary Artery Disease: A Review of Current Clinical Evidence and Recent Developments

被引：8

作者：

Yun, Chun-Ho ^{[1
]}

Hung, Chung-Lieh ^{[2
,3
]}

Wen, Ming-Shien ^{[4
]}

Wan, Yung-Liang ^{[5
]}

So, Aaron ^{[6
]}

机构：

[1] MacKay Mem Hosp, Dept Radiol, Taipei, Taiwan

[2] MacKay Mem Hosp, Dept Internal Med, Div Cardiol, Taipei, Taiwan

[3] Mackay Med Coll, Inst Biomed Sci, New Taipei, Taiwan

[4] Chang Gung Univ, Linkou Chang Gung Mem Hosp, Coll Med, Dept Cardiol, Taoyuan, Taiwan

[5] Chang Gung Univ, Linkou Chang Gung Mem Hosp, Coll Med, Dept Med Imaging & Intervent, 5,Fuxing St, Taoyuan 333423, Taiwan

[6] Univ Western Ontario, Lawson Hlth Res Inst, Imaging Program, Dept Med Biophys, London, ON, Canada

来源：

KOREAN JOURNAL OF RADIOLOGY | 2021年 / 22卷 / 11期

关键词：

CT perfusion; CT fractional flow reserve; CT angiography; Coronary artery disease; COMPUTED-TOMOGRAPHY ANGIOGRAPHY; DUAL-ENERGY CT; DIAGNOSTIC PERFORMANCE; BLOOD-FLOW; CARDIAC CT; ACCURACY; STENOSIS; QUANTIFICATION; MULTICENTER; FFR;

D O I：

10.3348/kjr.2020.1277

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Coronary computed tomography angiography (CCTA) is routinely used for anatomical assessment of coronary artery disease (CAD). However, invasive measurement of fractional flow reserve (FFR) is the current gold standard for the diagnosis of hemodynamically significant CAD. CT-derived FFRCT and CT perfusion are two emerging techniques that can provide a functional assessment of CAD for risk stratification and clinical decision making. Several clinical studies have shown that the diagnostic performance of concomitant CCTA and functional CT assessment for detecting hemodynamically significant CAD is at least non-inferior to that of other routinely used imaging modalities. This article aims to review the current clinical evidence and recent developments in functional CT techniques.

引用

页码：1749 / 1763

页数：15

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