Value of the CRP-albumin ratio in patients with resectable pancreatic cancer

被引：1
作者：
Arakawa, Yusuke [1 ]
Miyazaki, Katsuki [1 ]
Yoshikawa, Masato [1 ]
Yamada, Shinichiro [1 ]
Saito, Yu [1 ]
Ikemoto, Tetsuya [1 ]
Imura, Satoru [1 ]
Morine, Yuji [1 ]
Shimada, Mitsuo [1 ]
机构：
[1] Tokushima Univ, Inst Hlth Biosci, Dept Digest Surg & Transplantat, Tokushima, Japan
来源：
JOURNAL OF MEDICAL INVESTIGATION | 2021年 / 68卷 / 3-4期
关键词：
Pancreas cancer; C-reactive protein; albumin; C-REACTIVE PROTEIN; NEUTROPHIL-LYMPHOCYTE; PROTEIN/ALBUMIN RATIO; CURATIVE RESECTION; PROGNOSTIC SCORE; SURGERY; PREDICTORS; SURVIVAL;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Background : The C-reactive protein (CRP)-albumin ratio (CAR) was reported as a prognostic factor of resectable hepatocellular carcinoma. The aim of this study was to analyse the significance of CAR in resectable pancreatic cancer. Patients and Methods : 163 patients with curative resection for pancreatic cancer were enrolled in this retrospective study. Cases of non-curative resection were excluded. The CAR was calculated with the preoperative plasma CRP and albumin values, with a cut-off value of 0.06, as calculated in a previous report. Results : Patients in the low CAR group had significantly better overall survival (OS) and disease-free survival (DFS) compared with the high CAR group (P < 0.05). On multivariate analysis, for high CAR, CA19-9 300 U/ml and receipt of adjuvant chemotherapy were independent risk factors for OS and DFS. High CAR was significantly associated with advanced T stage. Conclusion : The CAR might be a prognostic factor for patients with resectable pancreatic cancer.
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页码：244 / 248
页数：5
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