Comparison of early pregnancy and neonatal outcomes after frozen and fresh embryo transfer in ART cycles

被引：69
作者：
Aflatoonian, Abbas [1 ]
Moghaddam, Fatemeh Mansoori [1 ]
Mashayekhy, Mehri [1 ]
Mohamadian, Farnaz [1 ]
机构：
[1] Shahid Sadoughi Univ Med Sci, Dept Obstet & Gynecol, Res & Clin Ctr Infertil, Safaieh 8916877391, Yazd, Iran
来源：
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2010年 / 27卷 / 12期
关键词：
Frozen-thawed embryo transfer; Fresh embryo transfer; Pregnancy outcome; Neonatal outcome; IN-VITRO FERTILIZATION; ASSISTED REPRODUCTIVE TECHNOLOGY; INTRACYTOPLASMIC SPERM INJECTION; LOW-BIRTH-WEIGHT; CRYOPRESERVED EMBRYOS; CHILDREN BORN; IVF CYCLES;
D O I：
10.1007/s10815-010-9470-z
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Purpose Frozen embryo transfer (FET) has no clear negative impact on neonatal outcome compared with fresh embryo transfer (ET) and appears to result in similar or even better neonatal outcome. The objective of this study was to compare early pregnancy outcome and neonatal health of children born after FET and fresh ET. Methods In this study early pregnancy and neonatal outcomes after FET (n = 200) and fresh ET (n = 500) were compared. Results For early pregnancy, biochemical pregnancy was comparable between FET and fresh ET groups. Spontaneous abortion was significantly higher in FET (14.5%) than fresh ET group (9%). Neonatal outcome was comparable between both groups except for lower live birth rate in FET (55%) versus fresh ET group (66%). Conclusion FET has similar neonatal outcome in terms of prematurity, low birth weight, stillbirth, neonatal death and major malformation compared with fresh ET.
引用
收藏
页码：695 / 700
页数：6
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