Hydrogen-Transfer-Mediated N-Arylation of Naphthols Using Indolines as Hydrogen Donors

被引：16

作者：

Chen, Xiuwen ^{[1
]}

Yang, Zhihai ^{[1
]}

Chen, Xuyan ^{[1
]}

Liang, Wanyi ^{[1
]}

Zhu, Zhongzhi ^{[1
]}

Xie, Feng ^{[1
]}

Li, Yibiao ^{[1
]}

机构：

[1] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 02期

关键词：

COUPLING REACTIONS; AROMATIC-AMINES; ALKYLATION; ACCESS; FUNCTIONALIZATION; CONSTRUCTION; ALKALOIDS; RECEPTOR; PHENOLS; ANALOGS;

D O I：

10.1021/acs.joc.9b02558

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Using a hydrogen-transfer-mediated activation mode, we report a new catalytic system for the transfer hydrogenation of naphthols. In the presence of the Pd/C catalyst and base, various naphthols reacted with indolines to afford N-aryl-substituted heterocyclic compounds. Indolines were found to act as novel hydrogen donors for naphthols under palladium catalysis. This method features good functional tolerance, operational simplicity, and a readily available catalyst.

引用

页码：508 / 514

页数：7

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