The First Autosomal STR Population Data of Kinh Ethinic Group in Vietnam by Using Massively Parallel Sequencing

被引：1

作者：

Pham, N. S. ^{[1
,2
,3
]}

Tran, H. L. ^{[1
]}

Nguyen, T. H. T. ^{[1
]}

Nguyen, V. H. ^{[3
]}

Hoang, H. ^{[1
]}

Tung, Q. N. ^{[1
]}

Phi, Q. T. ^{[1
,2
]}

机构：

[1] Vietnam Acad Sci & Technol, Inst Biotechnol, Hanoi 10000, Vietnam

[2] Grad Univ Sci & Technol, Vietnam Acad Sci & Technol, Hanoi 10000, Vietnam

[3] Minist Publ Secur, Inst Forens Sci, Hanoi 10000, Vietnam

来源：

RUSSIAN JOURNAL OF GENETICS | 2021年 / 57卷 / 08期

关键词：

massively parallel sequencing; autosomal short tandem repeats; Kinh population; LOCI;

D O I：

10.1134/S102279542108010X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Applications of massively parallel sequencing (MPS) in forensic genetics have allowed to exploit the true variation in core forensic STR loci, discover previously unknown STR alleles, aid mixture interpretation and will increase the statistical weight of the evidences. The worldwide populations database is exceedingly important in order to perform statistical calculations. In this study, we firstly present the population data for 27 autosomal STR loci of 148 Kinh ethnic individual living in Vietnam by using a MPS based on Illumina MiSeq platform. By using the largest number of markers for now, we indicated an increase in number of detected alleles as well. The combined match probability and power of exclusion reached 4.02E-30 and 0.999999999955384, respectively. The used markers are also demonstrated valuable in ancestry tracking of different human origins.

引用

页码：985 / 988

页数：4

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